Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
0.600 Biomarker disease BEFREE However, a number of distinct genetic defects including in inducible co-stimulator (ICOS), B-cell-activating factor receptor (BAFFR) and transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) have been identified in a minority of patients with CVID. 26096648 2015
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
0.600 AlteredExpression disease BEFREE BAFF-R levels inversely correlated with serum BAFF concentration both in CVID and healthy subjects. 24809296 2014
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
0.600 GeneticVariation disease BEFREE B lymphocyte subpopulations, previously defined classification schemes (Freiburg, Paris, EuroClass), TNFRSF13B (TACI), TNFRSF13C (BAFF-R), TNFSF13 (APRIL) gene mutations, CTLA-4 and ICOS gene polymorphisms were analyzed in 25 common variable immunodeficiency (CVID) patients and 25 healthy controls. 22699762 2012
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
0.600 GeneticVariation disease BEFREE The candidate gene approach has led to the detection of associations between common variable immunodeficiency (CVID) and mutations in the genes TACI, ICOS, BAFF-R, CD19, CD20, and CD81. 21905497 2011
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
0.600 GeneticVariation disease BEFREE New gene defects associated with a CVID phenotype have been described in BAFF-R, CD81, and CD20 in single consanguineous families. 20864887 2010
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
0.600 GeneticVariation disease BEFREE Analyzing BAFF-R expression and BAFF-binding to B cells in common variable immunodeficiency (CVID) patients, we identified two siblings carrying a homozygous deletion in the BAFF-R gene. 19666484 2009
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
0.600 Biomarker disease BEFREE In addition, the flowcytometric analysis of the inducible costimulator on activated T cells, CD19 and BAFF-R on B cells are valid screening methods for three of the four known genetic defects associated with CVID. 18561200 2008
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
0.600 AlteredExpression disease BEFREE To clarify the pathogenesis of CVID and IgAD of Japanese patients, we investigated the mutations of TNF family members TACI, APRIL, B-cell activating factor (BAFF), B-cell maturation antigen (BCMA) and BAFF receptor (BAFF-R) genes and the expression levels of BAFF and APRIL in patients with CVID, IgAD and X-linked agammaglobulinaemia (XLA). 18204790 2008
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
0.600 GeneticVariation disease BEFREE To test this hypothesis, we sequenced the BAFF-R gene in 48 patients with common variable immunodeficiency (CVID) along with 57 healthy controls. 16160919 2005
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
0.600 GeneticVariation disease LHGDN To test this hypothesis, we sequenced the BAFF-R gene in 48 patients with common variable immunodeficiency (CVID) along with 57 healthy controls. 16160919 2005
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
0.600 Biomarker disease BEFREE The recent discovery of genetic defects in the tumour necrosis factor receptor superfamily members TACI and BAFF receptor in patients with common variable immunodeficiency denotes further advances in this field. 16264328 2005
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
0.600 Biomarker disease CTD_human
Entrez Id: 115650
Gene Symbol: TNFRSF13C
TNFRSF13C
0.600 GermlineCausalMutation disease ORPHANET