Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
0.130 Biomarker disease BEFREE We analyzed whether there is an association between Tregs cells (CD4+CD25+CD127<sup>low</sup> and CD4+CD25+FoxP3+); memory T cells (CD4+CD45RO+); memory B cells (CD19+CD27-IgD-); and CD21<sup>low</sup> B cells (CD19+CD38<sup>low</sup>CD21<sup>low</sup>); as well as autoimmune manifestations in 36 patients with CVID (25 women and 11 men, mean age 24 years), all by flow cytometry. 31103252 2020
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
0.130 GeneticVariation disease GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688 2015
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
0.130 Biomarker disease BEFREE Frequency and expression of inhibitory markers of CD4(+) CD25(+) FOXP3(+) regulatory T cells in patients with common variable immunodeficiency. 23432692 2013
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
0.130 Biomarker disease BEFREE In conclusion, these data suggest compromised homeostasis of CD4(+)CD25(HIGH)FOXP3(+) cells in a subset of CVID patients with autoimmunity, and may implicate Treg cells in pathological mechanisms of CVID. 19394278 2009