Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 345
Gene Symbol: APOC3
APOC3
0.400 GeneticVariation disease BEFREE In humans, loss-of-function mutations in APOC3 are associated with reduced plasma TG levels and reduced risk for ischemic vascular disease and coronary heart disease. 26435212 2016
Entrez Id: 345
Gene Symbol: APOC3
APOC3
0.400 GeneticVariation disease BEFREE Association between apolipoprotein C3 Sst I, T-455C, C-482T and C1100T polymorphisms and risk of coronary heart disease. 24430880 2016
Entrez Id: 345
Gene Symbol: APOC3
APOC3
0.400 Biomarker disease CTD_human Common variants associated with plasma triglycerides and risk for coronary artery disease. 24097064 2014
Entrez Id: 345
Gene Symbol: APOC3
APOC3
0.400 Biomarker disease BEFREE Synergistic effect between lipoprotein lipase and apolipoprotein C3 genes in determining the severity of coronary artery disease. 23377670 2013
Entrez Id: 345
Gene Symbol: APOC3
APOC3
0.400 Biomarker disease BEFREE Apolipoprotein C-III (apoC-III) inhibits triglyceride hydrolysis and has been implicated in coronary artery disease. 19074352 2009
Entrez Id: 345
Gene Symbol: APOC3
APOC3
0.400 GeneticVariation disease BEFREE Synergistic effects of the apolipoprotein E epsilon3/epsilon2/epsilon4, the cholesteryl ester transfer protein TaqIB, and the apolipoprotein C3 -482 C>T polymorphisms on their association with coronary artery disease. 18289550 2008
Entrez Id: 345
Gene Symbol: APOC3
APOC3
0.400 GeneticVariation disease BEFREE The -1131 T>C and S19W APOA5 gene polymorphisms are associated with high levels of triglycerides and apolipoprotein C-III, but not with coronary artery disease: an angiographic study. 16682041 2007
Entrez Id: 345
Gene Symbol: APOC3
APOC3
0.400 GeneticVariation disease BEFREE APOC3 polymorphisms were associated with lipid parameters and coronary artery disease in several populations but not all. 17367769 2007
Entrez Id: 345
Gene Symbol: APOC3
APOC3
0.400 GeneticVariation disease BEFREE The multivariate model included 512 men with coronary artery disease from the REGRESS study who were completely genotyped for eight polymorphisms selected in the univariate procedure (ie, APOA1 G(-75)A, ABCA1 C(-477)T, ABCA1 G1051A, APOC3 T3206G, APOE Arg158Cys, LIPC C(-514)T, LPL Asn291Ser and LPL Ser447Stop). 15657615 2005
Entrez Id: 345
Gene Symbol: APOC3
APOC3
0.400 GeneticVariation disease BEFREE ApoC-III gene polymorphisms and risk of coronary artery disease. 12235176 2003
Entrez Id: 345
Gene Symbol: APOC3
APOC3
0.400 GeneticVariation disease BEFREE Association of the Sst-I polymorphism at the APOC3 gene locus with variations in lipid levels, lipoprotein subclass profiles and coronary heart disease risk: the Framingham offspring study. 11500189 2001
Entrez Id: 345
Gene Symbol: APOC3
APOC3
0.400 Biomarker disease BEFREE Therefore, VLDL particles with apoC-III may play a central role in identifying the high risk of coronary heart disease in hypertriglyceridemia, but their substantial prevalence in normolipidemics may be of clinical significance as well. 11483625 2001
Entrez Id: 345
Gene Symbol: APOC3
APOC3
0.400 GeneticVariation disease BEFREE Within the apolipoprotein A-I-C-III-A-IV gene cluster, the Ssti polymorphism in the 3' untranslated region of the apolipoprotein C-III gene is the variant site most consistently and strongly associated with raised plasma triglyceride levels and coronary artery disease. 9211063 1997