Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Interaction between eNOS gene polymorphism and current smoking on susceptibility to coronary heart disease in Chinese people. 31567371 2020
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE The contribution of NOS3 variants to coronary artery disease: A combined genetic epidemiology and computational biochemistry perspective. 30447355 2019
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Odds ratios with 95% confidence intervals were used to evaluate associations between endothelial nitric oxide synthase polymorphisms and coronary artery disease. 30789045 2019
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE The association between an endothelial nitric oxide synthase gene polymorphism and coronary heart disease in young people and the underlying mechanism. 29359785 2018
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 Biomarker disease BEFREE Association between NOS3 <i>G894T, T-786C</i> and 4a/4b Variants and Coronary Artery Diseases in Iranian Population. 30788304 2018
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Assessment of the role of plasma nitric oxide levels, T-786C genetic polymorphism, and gene expression levels of endothelial nitric oxide synthase in the development of coronary artery disease. 28461820 2017
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Association of the Endothelial Nitric Oxide Synthase Gene T786C Polymorphism with In-Stent Restenosis in Chinese Han Patients with Coronary Artery Disease Treated with Drug-Eluting Stent. 28129392 2017
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Association Patterns of Endothelial Nitric Oxide Synthase Gene (NOS3) Variant Glu298Asp with Blood Pressure and Serum Lipid Levels in Subjects with Coronary Artery Disease from Pakistan. 28620990 2017
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Association between NOS3 genetic variants and coronary artery disease in the Han population. 27323132 2016
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Association of Cholesteryl Ester Transfer Protein and Endothelial Nitric Oxide Synthase Gene Polymorphisms With Coronary Artery Disease in the Multi-Ethnic Malaysian Population. 25667236 2016
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE In this study, we investigated the association between -786T/C polymorphism of the endothelial nitric oxide (NOS3) gene in which thymidine is replaced by a cytosine at nucleotide -786 (rs 2070744) and coronary collateral circulation (CCC) in patients with stable coronary artery disease. 26864067 2016
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE The results indicated that female sex, diabetes, and mutation in -786T/C eNOS gene correlate with ACh-provoked myocardial ischemia in patients with coronary spasm. 26656861 2015
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE We investigated the association of the T-786C single nucleotide polymorphism (SNP) of the endothelial nitric oxide synthase gene (NOS3), which is characterised by reduced expression of the enzyme in response to shear stress or interleukin-10 stimulation and significantly associated with coronary heart disease or rheumatoid arthritis, with the occurrence of isolated polymyalgia rheumatica. 26314610 2015
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Genetic etiology of coronary artery disease considering NOS 3 gene variant rs1799983. 25057159 2015
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Association between the - 786T>C 1polymorphism in the promoter region of endothelial nitric oxide synthase (eNOS) and risk of coronary artery disease: a systematic review and meta-analysis. 24135644 2014
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Association of endothelial nitric oxide synthase gene polymorphisms with coronary artery disease: an updated meta-analysis and systematic review. 25409023 2014
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Endothelial nitric oxide synthase (eNOS) 4b/a gene polymorphisms and coronary artery disease: evidence from a meta-analysis. 24810690 2014
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 Biomarker disease BEFREE Gene-gene interaction of ACE I/D, endothelial nitric oxide synthase 4 a/b and ApoE does not affect coronary artery disease severity. 24913112 2014
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE The nitric oxide (NO) synthase 3 (NOS3) gene is responsible for the synthesis of endothelial NO synthase (eNOS) in humans and some genetic polymorphisms are considered "polymorphisms associated with risk" for the development of coronary artery diseases, such as acute coronary syndrome. 23918902 2014
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Association between the endothelial nitric oxide synthase gene Glu298Asp polymorphism and coronary heart disease: a meta‑analysis of 39 case‑control studies. 23443250 2013
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Association of the genetic variants of endothelial nitric oxide synthase gene with angiographically defined coronary artery disease and myocardial infarction in South Indian patients with type 2 diabetes mellitus. 23182401 2013
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Association of endothelial nitric oxide synthase gene variant (G894T) with coronary artery disease in Western Iran. 21602253 2012
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE The G894T polymorphism on endothelial nitric oxide synthase gene is associated with increased coronary heart disease among Asia population: evidence from a Meta analysis. 22417945 2012
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE Strong interaction between T allele of endothelial nitric oxide synthase with B1 allele of cholesteryl ester transfer protein TaqIB highly elevates the risk of coronary artery disease and type 2 diabetes mellitus. 23157875 2012
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.400 GeneticVariation disease BEFREE In conclusion, the protective HO1 promoter polymorphism correlates with a lower coronary artery plaque burden, whereas the protective ENOS 894 G/T polymorphism seems to favourably influence changes of coronary artery plaque composition during statin therapy, but has no significant correlation to the magnitude of coronary atherosclerosis. 22123460 2011