Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9365
Gene Symbol: KL
KL
0.400 AlteredExpression disease BEFREE A total of 3555 patients with stable ischaemic heart disease and left ventricular ejection fraction > 40% enrolled in the PEACE trial of trandolapril vs. placebo had Klotho levels drawn at randomization. 30773798 2019
Entrez Id: 9365
Gene Symbol: KL
KL
0.400 Biomarker disease BEFREE There are a lot of evidences that Klotho deficiency correlates with the occurrence and development of coronary artery disease, atherosclerosis, myocardial infarction, and left ventricular hypertrophy. 30671457 2018
Entrez Id: 9365
Gene Symbol: KL
KL
0.400 GeneticVariation disease BEFREE In multiple regression analysis, a high Klotho level was associated with a reduced risk of developing coronary artery disease and cerebrovascular accidents. 30048945 2018
Entrez Id: 9365
Gene Symbol: KL
KL
0.400 GeneticVariation disease BEFREE Association of Klotho gene polymorphism with hypertension and coronary artery disease in an Iranian population. 30547758 2018
Entrez Id: 9365
Gene Symbol: KL
KL
0.400 Biomarker disease BEFREE Our results suggest that serum Klotho is higher in individuals with a clinical history of myocardial infarction but not with a history of coronary artery disease or stroke. 28076518 2016
Entrez Id: 9365
Gene Symbol: KL
KL
0.400 AlteredExpression disease BEFREE Moreover, vascular expression levels of Klotho were related with the incidence of diabetes mellitus and coronary artery disease. 26538295 2016
Entrez Id: 9365
Gene Symbol: KL
KL
0.400 Biomarker disease BEFREE Reduced Klotho is associated with the presence and severity of coronary artery disease. 24165855 2014
Entrez Id: 9365
Gene Symbol: KL
KL
0.400 GeneticVariation disease BEFREE Genetic variation in klotho has been reported to be a risk factor for coronary artery disease and ischemic stroke. 23993164 2013
Entrez Id: 9365
Gene Symbol: KL
KL
0.400 GeneticVariation disease BEFREE Klotho gene polymorphism may be a genetic risk factor for atherosclerotic coronary artery disease but not for vasospastic angina in Japanese. 16579981 2006
Entrez Id: 9365
Gene Symbol: KL
KL
0.400 GeneticVariation disease BEFREE The differential effects of age on the association of KLOTHO gene polymorphisms with coronary artery disease. 16979405 2006
Entrez Id: 9365
Gene Symbol: KL
KL
0.400 GeneticVariation disease BEFREE We previously identified a functional variant of KLOTHO, termed KL-VS, that is associated with human aging and early-onset occult coronary artery disease. 15677572 2005
Entrez Id: 9365
Gene Symbol: KL
KL
0.400 GeneticVariation disease BEFREE KLOTHO allele status and the risk of early-onset occult coronary artery disease. 12669274 2003
Entrez Id: 9365
Gene Symbol: KL
KL
0.400 Biomarker disease CTD_human KLOTHO allele status and the risk of early-onset occult coronary artery disease. 12669274 2003