Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
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0.450 | AlteredExpression | disease | BEFREE | Mice with a coronary artery disease-linked mutation in Wnt-coreceptor LRP6 (LDL receptor-related protein 6) exhibit vascular smooth muscle cell dedifferentiation and obstructive coronary artery disease, which are paradoxically associated with reduced TCF7L2 expression. | 30567484 | 2019 | ||||
|
0.450 | Biomarker | disease | CTD_human | Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. | 28869590 | 2017 | ||||
|
0.450 | GeneticVariation | disease | GWASCAT | Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. | 27790247 | 2016 | ||||
|
0.450 | Biomarker | disease | BEFREE | Impaired LRP6-TCF7L2 Activity Enhances Smooth Muscle Cell Plasticity and Causes Coronary Artery Disease. | 26489464 | 2015 | ||||
|
0.450 | GeneticVariation | disease | BEFREE | Moreover, we observed associations between TCF7L2 variants and the following diabetic complications: diabetic retinopathy, cardiovascular disease and coronary artery disease. | 22843023 | 2013 | ||||
|
0.450 | GeneticVariation | disease | GWASDB | Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. | 21347282 | 2011 | ||||
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0.450 | GeneticVariation | disease | BEFREE | This study aimed to evaluate the association between TCF7L2 polymorphism rs7903146 and coronary artery disease in diabetic and non-diabetic subjects. | 19924244 | 2009 | ||||
|
0.450 | GeneticVariation | disease | LHGDN | TCF7L2 rs7903146 T allele is associated with a 1.57 increased risk for type 2 diabetes in a Brazilian cohort of patients with known coronary heart disease. | 19055834 | 2008 | ||||
|
0.450 | GeneticVariation | disease | BEFREE | TCF7L2 rs7903146 T allele is associated with a 1.57 increased risk for type 2 diabetes in a Brazilian cohort of patients with known coronary heart disease. | 19055834 | 2008 |