Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 22802
Gene Symbol: CLCA4
CLCA4
0.340 AlteredExpression disease BEFREE The apparently pig-specific duplication of the CLCA4 gene with unique expression of the CLCA4b protein variant in intestinal crypt epithelial cells where the porcine CFTR is also present raises the question of whether it may modulate the porcine CF phenotype. 26474299 2015
Entrez Id: 22802
Gene Symbol: CLCA4
CLCA4
0.340 GeneticVariation disease BEFREE Refined analysis of the CLCA4 association signal among F508del homozygous CF patients who exhibit either no, CFTR-mediated or Ca(2+)-mediated residual chloride conductance revealed that allele distributions for markers rs11807298-rs113894048-rs6684219 differed significantly among these three patient groups. 23073314 2013
Entrez Id: 22802
Gene Symbol: CLCA4
CLCA4
0.340 GermlineModifyingMutation disease ORPHANET Refined analysis of the CLCA4 association signal among F508del homozygous CF patients who exhibit either no, CFTR-mediated or Ca(2+)-mediated residual chloride conductance revealed that allele distributions for markers rs11807298-rs113894048-rs6684219 differed significantly among these three patient groups. 23073314 2013
Entrez Id: 22802
Gene Symbol: CLCA4
CLCA4
0.340 Biomarker disease BEFREE The results may add to the understanding of species-specific differences in the CF phenotype and support the notion that the CF pig model may be more suitable than murine models to study the role of hCLCA4. 22205680 2012
Entrez Id: 22802
Gene Symbol: CLCA4
CLCA4
0.340 Biomarker disease LHGDN The CLCA gene locus as a modulator of the gastrointestinal basic defect in cystic fibrosis. 15490240 2004