Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4233
Gene Symbol: MET
MET
0.100 GeneticVariation disease BEFREE This study analyses distribution patterns of the delta F508 mutation of the cystic fibrosis transmembrane conductance regulator gene (CFTR) gene and the cystic fibrosis (CF)-linked marker loci MET, D7S23, D7S399, and D7S8 in a sample of 167 (116 complete) CF families from Bohemia and Moravia (Czechoslovakia). 2210755 1990
Entrez Id: 4233
Gene Symbol: MET
MET
0.100 Biomarker disease BEFREE Our previous linkage analysis suggested that the DNA segment D7S122 is located between MET and D7S8, the two genetic markers that are thought to flank the cystic fibrosis locus (CF). 2589321 1989
Entrez Id: 4233
Gene Symbol: MET
MET
0.100 GeneticVariation disease BEFREE Data for XV2c and MET markers in 16 American black patients and their families revealed a different haplotype distribution and LD pattern with the CF locus. 2563631 1989
Entrez Id: 4233
Gene Symbol: MET
MET
0.100 GeneticVariation disease BEFREE In a 1:4 risk family, the usefulness of probes at the D7S23 locus for prenatal diagnosis of cystic fibrosis is discussed by comparison with probes at the MET, D7S8, and D7S18 loci that did not allow accuracy in this family. 2569290 1989
Entrez Id: 4233
Gene Symbol: MET
MET
0.100 Biomarker disease BEFREE We have demonstrated the assignments of two gene loci (COLIA2, MET) and two noncoding DNA markers (D7S13, D7S8) to owl monkey chromosome 14 (K-VI) by hybridizing DNA probes from the cystic fibrosis (CF) region of human chromosome 7q21-32 to panels of rodent-owl monkey somatic cell hybrids. 2613227 1989
Entrez Id: 4233
Gene Symbol: MET
MET
0.100 GeneticVariation disease BEFREE The frequency distribution of CF haplotypes in the Hutterite sample differs notably from those of larger agglomerates of family data from collaborative studies, with respect to D7S8, MET haplotypes, and D7S23 haplotypes. 2563632 1989
Entrez Id: 4233
Gene Symbol: MET
MET
0.100 Biomarker disease BEFREE Together with the previously identified markers, MET, D7S8, D7S13 and D7S16, these new markers should provide a fine genetic and physical map for the chromosomal region surrounding CF. 2900520 1988
Entrez Id: 4233
Gene Symbol: MET
MET
0.100 Biomarker disease BEFREE Linkage analysis in families segregating for CF suggested that the most likely location of the CF gene on this map is between MET and D7S8. 2892400 1988
Entrez Id: 4233
Gene Symbol: MET
MET
0.100 Biomarker disease BEFREE These data and in situ chromosomal hybridization analysis would indicate that MET and, therefore, the cystic fibrosis locus are located at bands q31-q32 on human chromosome 7. 3282234 1988
Entrez Id: 4233
Gene Symbol: MET
MET
0.100 GeneticVariation disease BEFREE Preliminary large-scale restriction mapping of the fragment showed that the NotI polymorphic site is 200-370 kb distant from the MET locus; thus it defines a new polymorphic locus in the CF region. 2892401 1988
Entrez Id: 4233
Gene Symbol: MET
MET
0.100 GeneticVariation disease BEFREE Three additional DNA polymorphisms in the met gene and D7S8 locus: use in prenatal diagnosis of cystic fibrosis. 2888841 1987
Entrez Id: 4233
Gene Symbol: MET
MET
0.100 GeneticVariation disease BEFREE There are significant allelic associations between CF, MET, D7S8 and D7S16; these allelic associations affect the risk of random individuals to be carriers of CF. 2886421 1987
Entrez Id: 4233
Gene Symbol: MET
MET
0.100 Biomarker disease BEFREE Two families with a crossover between MET and the CF phenotype were detected. 2888722 1987
Entrez Id: 4233
Gene Symbol: MET
MET
0.100 Biomarker disease BEFREE Based on the result from one family, MET appears to be more proximal to the centromere than CF. 3467587 1986
Entrez Id: 4233
Gene Symbol: MET
MET
0.100 GeneticVariation disease BEFREE A collaborative study involving seven research groups provided an opportunity to investigate the linkage relationships between cystic fibrosis and two DNA marker loci, MET and pJ3.11 (D7S8), on an extended sample of 211 tested families. 3026171 1986
Entrez Id: 4233
Gene Symbol: MET
MET
0.100 Biomarker disease BEFREE Among the 79 affected children, no recombinants were detected between the disease and the markers MET and pJ3.11, previously shown to be linked to CF. 3026172 1986
Entrez Id: 4233
Gene Symbol: MET
MET
0.100 Biomarker disease BEFREE Analysis by the seriation method indicates the order COL-pJ3.11-CF-MET. 3026173 1986
Entrez Id: 4233
Gene Symbol: MET
MET
0.100 GeneticVariation disease BEFREE Further linkage studies, now involving 22 families, have confirmed the tight linkage of cystic fibrosis to the MET and D7S8 loci. 2879438 1986