Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1652
Gene Symbol: DDT
DDT
0.010 Biomarker disease BEFREE Preclinical data show conflicting results on the role of endogenous MIF and DDT in depression. 31818772 2020
Entrez Id: 79947
Gene Symbol: DHDDS
DHDDS
0.010 GeneticVariation disease BEFREE Latent structure of the CPT among treatment-seeking smokers with depression and its predictive validity on smoking abstinence. 30371826 2020
Entrez Id: 4747
Gene Symbol: NEFL
NEFL
0.010 Biomarker disease BEFREE Models examine the relationship of bodily pain, injury as a reason for retirement or not re-signing with a team, length of NFL career, sociodemographic characteristics, chronic conditions, and functional limitations to depression. 31522600 2020
Entrez Id: 574506
Gene Symbol: MIR503
MIR503
0.010 AlteredExpression disease BEFREE Subsequent rescue assay revealed that down-regulation of miR-503 or restoration of SHOX2 canceled IGF2-AS depletion-induced depression in proliferation and motility of BGC823 and SGC7901 cells. 31183590 2020
Entrez Id: 103021164
Gene Symbol: CASC21
CASC21
0.010 Biomarker disease BEFREE Moreover, CASC21 knockdown displayed significant depression in cell viability, proliferation, migration, and invasion in colorectal cancer cells, as well as EMT process, while cell apoptosis was promoted by regulating the Bcl-2/Bax axis and Caspase cascade. 31731190 2020
Entrez Id: 6050
Gene Symbol: RNH1
RNH1
0.010 Biomarker disease BEFREE Patients with depression or anxiety presented significantly higher PRI(R)s [depressed 65% vs. non-depressed 57% (P = 0·015); anxious 65% vs. nonanxious 57% (P = 0·004)]. 30919930 2020
Entrez Id: 7259
Gene Symbol: TSPYL1
TSPYL1
0.010 GeneticVariation disease BEFREE Our findings suggest that genetic variation in TSPYL genes may be novel indicators for baseline severity of depression and SSRI poor response. 31628858 2020
Entrez Id: 6492
Gene Symbol: SIM1
SIM1
0.010 GeneticVariation disease BEFREE Susceptibility signature shared Rtn1, Zdhhc5, Igsf6, and Sim1 genes with the latest depression GWAS meta-analysis, while antidepressant resistance signature shared Ctnnd1, Rbms3, Atp1a3, and Pla2r1 genes. 31813757 2020
Entrez Id: 1524
Gene Symbol: CX3CR1
CX3CR1
0.010 Biomarker disease BEFREE Involvement of CX3CL1/CX3CR1 in Depression and Cognitive Impairment Induced by Chronic Unpredictable Stress and Relevant Underlying Mechanism. 31765724 2020
Entrez Id: 3895
Gene Symbol: KTN1
KTN1
0.010 Biomarker disease BEFREE We have also demonstrated that KNT-127 showed potent and rapid antidepressant-like effects in rat models of depression. 31654658 2020
Entrez Id: 6261
Gene Symbol: RYR1
RYR1
0.010 Biomarker disease BEFREE Post-hoc comparisons with Bonferroni adjustment (α=0.05/3 = 0.0167) showed that well-adherent ART users had lower scores on anxiety (p=0.006) and higher scores on MHS (p=0.007), but no difference was found for depression (p=0.023). 31072130 2020
Entrez Id: 64806
Gene Symbol: IL25
IL25
0.010 AlteredExpression disease BEFREE Using linear regression modelling, we identified that levels of IL-22 and IL-17E are positively and significantly associated with depression. 30980732 2020
Entrez Id: 6517
Gene Symbol: SLC2A4
SLC2A4
0.010 Biomarker disease BEFREE In the case of the coexistence of depression and obesity, the most important changes were (1) the decrease in the membrane form of GLUT4, which may suggest weaker insulin action in the frontal cortex, and (2) the diminished GLP-1R, which could cause neurodegenerative changes in the hippocampus. 31782099 2020
Entrez Id: 51495
Gene Symbol: HACD3
HACD3
0.010 Biomarker disease BEFREE Magnetic resonance imaging (MRI) scans from 196 patients with MDD and 110 healthy participants were obtained as part of the first study in the Canadian Biomarker Integration Network in Depression program (CAN-BIND 1) in which patients were treated for 16 weeks with open-label medication. 31610545 2020
Entrez Id: 112476
Gene Symbol: PRRT2
PRRT2
0.010 Biomarker disease BEFREE The identification of these 15 differentially expressed proteins, including PRRT2, provides further insight into the treatment mechanism of SA for depression. 31762213 2020
Entrez Id: 335
Gene Symbol: APOA1
APOA1
0.010 GeneticVariation disease BEFREE Higher levels of apolipoprotein B, very-low-density lipoprotein cholesterol, triglycerides, diglycerides, total and monounsaturated fatty acids, fatty acid chain length, glycoprotein acetyls, tyrosine, and isoleucine and lower levels of high-density lipoprotein cholesterol, acetate, and apolipoprotein A1 were associated with increased odds of depression. 31635762 2020
Entrez Id: 51214
Gene Symbol: IGF2-AS
IGF2-AS
0.010 Biomarker disease BEFREE Subsequent rescue assay revealed that down-regulation of miR-503 or restoration of SHOX2 canceled IGF2-AS depletion-induced depression in proliferation and motility of BGC823 and SGC7901 cells. 31183590 2020
Entrez Id: 50616
Gene Symbol: IL22
IL22
0.010 AlteredExpression disease BEFREE Using linear regression modelling, we identified that levels of IL-22 and IL-17E are positively and significantly associated with depression. 30980732 2020
Entrez Id: 59342
Gene Symbol: SCPEP1
SCPEP1
0.010 Biomarker disease BEFREE Considering the application of the CD-RISC-10 in depression patients, the present study aimed to evaluate the psychometric properties, especially the measurement invariance, of the CD-RISC-10 in depressive patient sample. 31654919 2020
Entrez Id: 56994
Gene Symbol: CHPT1
CHPT1
0.010 GeneticVariation disease BEFREE Latent structure of the CPT among treatment-seeking smokers with depression and its predictive validity on smoking abstinence. 30371826 2020
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
0.010 AlteredExpression disease BEFREE During the 3-month follow-up, 76 patients were defined as depression (24.5%; 95% confidence interval [CI]: 17.9%-29.3%), and GDF-15 levels in those patients were nearly more than 1 time greater as compared with patients who were free of depression (P < 0.001). 31561112 2020
Entrez Id: 284654
Gene Symbol: RSPO1
RSPO1
0.010 Biomarker disease BEFREE The miscibility of curcumin and Eudragit RSPO and Eudragit RLPO were assessed by solubility parameter and melting point depression. 31809744 2020
Entrez Id: 79586
Gene Symbol: CHPF
CHPF
0.010 Biomarker disease BEFREE Sensitivity of CSS 2-item depression and 2-item anxiety risk scales were .91 and .92, respectively. 30980258 2020
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A
0.010 Biomarker disease BEFREE Sensitivity of CSS 2-item depression and 2-item anxiety risk scales were .91 and .92, respectively. 30980258 2020
Entrez Id: 84290
Gene Symbol: CAPNS2
CAPNS2
0.010 Biomarker disease BEFREE Sensitivity of CSS 2-item depression and 2-item anxiety risk scales were .91 and .92, respectively. 30980258 2020