Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 AlteredExpression disease BEFREE Data seem to suggest that lower levels of adiponectin, and higher levels of resistin can be predictive of a future diabetes in obese people, even years before the disease onset. 31811995 2020
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 Biomarker disease BEFREE The therapeutic potential of adiponectin regulation has received interest because of its association with diverse human disease conditions, such as diabetes, obesity, atherosclerosis, and cancer. 30672698 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 Biomarker disease BEFREE These observations are physiologically significant and critical when considering ways to harness the therapeutic potential of adiponectin for diabetes. 31310580 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 GeneticVariation disease BEFREE The aim of this study was to ascertain the polymorphic markers profile of ADIPOQ, KCNJ11 and TCF7L2 genes in Kyrgyz population and to analyze the association of polymorphic markers and combinations of ADIPOQ gene's G276T locus, KCNJ11 gene's Glu23Lys locus and TCF7L2 gene's VS3C>T locus with type two diabetes (T2D) in Kyrgyz population. 30467975 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 AlteredExpression disease BEFREE These results suggested that excess dietary iron leads to reduced mass, increased fasting glucose, decreased adiponectin level, and enhancement of insulin resistance, which indicated a multifactorial role of excess iron in the development of diabetes in the setting of obesity. 30027366 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 Biomarker disease BEFREE The combination of MASP, apolipoprotein E (apoE) and adiponectin improved diabetes prediction on top of both reference models, while prediabetes prediction was improved by MASP plus CRP on top of the HbA1c model. 30599058 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 AlteredExpression disease BEFREE The predictive effect of high-serum adiponectin level on mortality disappeared after adjusting for diabetes and cardiovascular disease. 29674409 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 Biomarker disease BEFREE Adiponectin, an adipokine secreted by adipocytes, exerts favorable effects in the milieu of diabetes and metabolic syndrome through its anti-inflammatory, antifibrotic, and antioxidant effects. 30974901 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 Biomarker disease BEFREE Adiponectin homolog novel osmotin protects obesity/diabetes-induced NAFLD by upregulating AdipoRs/PPARα signaling in ob/ob and db/db transgenic mouse models. 30473057 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 Biomarker disease BEFREE The Protective Role of Adiponectin for Lipoproteins in End-Stage Renal Disease Patients: Relationship with Diabetes and Body Mass Index. 30911344 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 GeneticVariation disease BEFREE E-selectin, (HR 1.19 [95% CI 1.06, 1.34]), adiponectin (0.84 [0.71, 0.99]) and tissue plasminogen activator (1.13 [1.03, 1.24]) were associated with incident diabetes in the placebo group, independent of diabetes risk factors. 30334082 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 Biomarker disease BEFREE Adiponectin is an adipokine that improves insulin sensitivity in obesity-related metabolic disorders, including diabetes, but its efficacy is unknown. 31048658 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 Biomarker disease BEFREE Adiponectin has also β cell protective effects and may prevent the development of diabetes. 30857216 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 GeneticVariation disease BEFREE Adjustment for liver fat and triacylglycerols, adiponectin and C-reactive protein substantially attenuated associations between height and diabetes risk, particularly among women. 31501920 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 Biomarker disease BEFREE The aim of this study was to evaluate adiponectin as a diagnostic marker of T2DM and diabetes control. 30069271 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 Biomarker disease BEFREE C1q/TNF-related protein 3 (CTRP3), a paralog of adiponectin, has been proposed to exert anti-apoptotic effects and to attenuate diabetes-related cardiac injuries. 29572383 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 Biomarker disease BEFREE Association of adiponectin with cognitive function precedes overt diabetes in the Brazilian Longitudinal Study of Adult Health: ELSA. 30002734 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 Biomarker disease BEFREE To evaluate the additional discriminatory performance of adiponectin, leptin, and their ratio in the identification of impaired glucose tolerance (IGT) in men and women without diabetes on top of conventional risk factors. 30399195 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 GeneticVariation disease BEFREE Association of genetic variants in RETN, NAMPT and ADIPOQ gene with glycemic, metabolic traits and diabetes risk in a Chinese population. 29101068 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 Biomarker disease BEFREE These results suggest significant associations between BCAA concentrations and those for adiponectin, leptin and HOMA2-IR in individuals without diabetes. 29348480 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 AlteredExpression disease BEFREE The results suggest that increasing adiponectin levels could be a therapeutic approach to restore hippocampal neurogenesis impairment in individuals with diabetes. 30333718 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 Biomarker disease BEFREE In fact, a positive, rather than the expected negative, relationship was reported between adiponectin and mortality rate across many clinical conditions, comprising diabetes. 29263167 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 Biomarker disease BEFREE Results The urinary adiponectin concentrations in patients with diabetes (3.3 ± 10.7 ng/mg creatinine) were significantly higher than those in obese subjects (0.54 ± 0.44; P < 0.01) and healthy subjects (0.46 ± 0.42; P < 0.001). 29199440 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 Biomarker disease BEFREE Logistic regression analysis showed that FINS, ADPN, HOMA-R, CPR, duration of diabetes mellitus and BMI had independently predictive value for diabetes complicated with CHD (P<0.05). 30186434 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.100 AlteredExpression disease BEFREE Plasma adiponectin levels and expression of its receptors, AdipoRs are decreased in obesity, which cause insulin resistance and diabetes. 30282888 2018