Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2
0.500 Biomarker disease RGD Early energy metabolism-related molecular events in skeletal muscle of diabetic rats: The effects of l-arginine and SOD mimic. 28483572 2017
Entrez Id: 836
Gene Symbol: CASP3
CASP3
0.500 Therapeutic disease RGD Berberine chloride ameliorates oxidative stress, inflammation and apoptosis in the pancreas of Streptozotocin induced diabetic rats. 28843149 2017
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.500 Biomarker disease CTD_human Antidiabetic effect of SN158 through PPARα/γ dual activation in ob/ob mice. 28242381 2017
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.500 Therapeutic disease RGD Modifications of expression of genes and proteins involved in DNA repair and nitric oxide metabolism by carbatonides [disodium-2,6-dimethyl-1,4-dihydropyridine- 3,5-bis(carbonyloxyacetate) derivatives] in intact and diabetic rats. 28976888 2017
Entrez Id: 8660
Gene Symbol: IRS2
IRS2
0.500 Biomarker disease CTD_human Resveratrol treatment restores peripheral insulin sensitivity in diabetic mice in a sirt1-independent manner. 25808216 2015
Entrez Id: 2876
Gene Symbol: GPX1
GPX1
0.500 Therapeutic disease RGD Effect of exercise training on liver antioxidant enzymes in STZ-diabetic rats. 25744399 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.500 Biomarker disease RGD Diabetes-induced oxidative DNA damage alters p53-p21CIP1/Waf1 signaling in the rat testis. 24828139 2015
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.500 Therapeutic disease CTD_human Reducing blood glucose levels in TIDM mice with an orally administered extract of sericin from hIGF-I-transgenic silkworm cocoons. 24632065 2014
Entrez Id: 857
Gene Symbol: CAV1
CAV1
0.500 Biomarker disease RGD Upregulation of caveolin-1 contributes to aggravated high-salt diet-induced endothelial dysfunction and hypertension in type 1 diabetic rats. 25086377 2014
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.500 Therapeutic disease RGD GABA tea prevents cardiac fibrosis by attenuating TNF-alpha and Fas/FasL-mediated apoptosis in streptozotocin-induced diabetic rats. 24374093 2014
Entrez Id: 2936
Gene Symbol: GSR
GSR
0.500 Therapeutic disease RGD Cardiac energy metabolism and oxidative stress biomarkers in diabetic rat treated with resveratrol. 25050809 2014
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.500 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 3667
Gene Symbol: IRS1
IRS1
0.500 Biomarker disease RGD Altered gene expression involved in insulin signaling pathway in type II diabetic osteoporosis rats model. 22820932 2013
Entrez Id: 6720
Gene Symbol: SREBF1
SREBF1
0.500 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.500 Biomarker disease CTD_human Resveratrol, an activator of SIRT1, restores erectile function in streptozotocin-induced diabetic rats. 23792339 2013
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.500 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
0.500 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.500 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.500 Biomarker disease RGD Regulation of matrix metalloproteinase-9 by epigenetic modifications and the development of diabetic retinopathy. 23423566 2013
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
0.500 Therapeutic disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 2309
Gene Symbol: FOXO3
FOXO3
0.500 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 2309
Gene Symbol: FOXO3
FOXO3
0.500 Biomarker disease CTD_human Resveratrol, an activator of SIRT1, restores erectile function in streptozotocin-induced diabetic rats. 23792339 2013
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.500 Biomarker disease CTD_human Protective effects of chronic resveratrol treatment on vascular inflammatory injury in streptozotocin-induced type 2 diabetic rats: Role of NF-kappa B signaling. 24513509 2013
Entrez Id: 26291
Gene Symbol: FGF21
FGF21
0.500 Therapeutic disease CTD_human Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial- and endoplasmic reticulum stress-dependent pathways in the mouse model. 23499715 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.500 Biomarker disease CTD_human Resveratrol, an activator of SIRT1, restores erectile function in streptozotocin-induced diabetic rats. 23792339 2013