Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.440 | GeneticVariation | disease | BEFREE | Importantly, genome-wide association studies showed that variations of GLIS3 are strongly associated with both type 1 diabetes (T1D) and type 2 diabetes (T2D) in multiple populations. | 27899417 | 2017 | ||||
|
0.440 | GeneticVariation | disease | BEFREE | Therefore, the aim of this study was to replicate the association of the rs10758593 and rs7020673 single nucleotide polymorphisms (SNPs) in the GLIS3 gene with T1DM in a Brazilian population. | 28597135 | 2017 | ||||
|
0.440 | Biomarker | disease | BEFREE | GLIS3 is a key transcription factor in insulin production and β-cell differentiation during embryonic development, which perturbation forms the basis of monogenic diabetes as well as its association with T1D. | 27035557 | 2016 | ||||
|
0.440 | GeneticVariation | disease | GWASCAT | Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers. | 25751624 | 2015 | ||||
|
0.440 | GeneticVariation | disease | BEFREE | The association analysis of the low-frequency variants revealed that only the A908V variant of GLIS3 was strongly associated with resistance to T1D (Haldane's odds ratio = 0.046, p = 8.21 × 10(-4), and pc=2.22 × 10(-2)). | 23856252 | 2013 | ||||
|
0.440 | GeneticVariation | disease | GWASDB | A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci. | 21980299 | 2011 | ||||
|
0.440 | Biomarker | disease | CTD_human | Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. | 19430480 | 2009 | ||||
|
0.440 | GeneticVariation | disease | GWASDB | Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. | 19430480 | 2009 | ||||
|
0.440 | GeneticVariation | disease | GWASCAT | Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. | 19430480 | 2009 |