Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.400 AlteredExpression disease BEFREE The hippocampal GFAP, synaptophysin and mGluR3 expressions where upregulated in PTZ rats with PFS history when compared to PTZ rats alone.These findings indicated that PFS may increase the severity of epilepsy and alter brain expression of GFAP, synaptophysin and mGluR3 proteins. 31837458 2020
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.400 AlteredExpression disease BEFREE Compared with miR-103a inhibitors alone, epilepsy rats treated with BDNF-siRNA combined with miR-103a inhibitors significantly increased expression of GFAP in hippocampal tissues of epilepsy rats, increased number of apoptotic neurons and significantly decreased the number of surviving neurons. 31049031 2019
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.400 Biomarker disease BEFREE The aim of the present study was to assess the expression of P2X7R, glutamate (GLU) and glial fibrillary acidic protein (GFAP) in the temporal neocortex and hippocampus of rats with lithium‑pilocarpine‑induced epilepsy as well as in patients with intractable TLE. 31059094 2019
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.400 Biomarker disease BEFREE The role of UCH-L1, MMP-9, and GFAP as peripheral markers of different susceptibility to seizure development in a preclinical model of epilepsy. 30952062 2019
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.400 AlteredExpression disease BEFREE Serum concentrations of HMGB1, IL-1β, S-100B, and GFAP were significantly higher in the epilepsy group within 24 hours of a seizure episode than in the control group. 30303442 2018
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.400 AlteredExpression disease BEFREE Nestin cells represented 29% of the hippocampal proliferative fraction in epilepsy cases; 20% co-expressed βIII tubulin in culture compared with 28% with GFAP. 28925561 2018
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.400 Biomarker disease BEFREE Tsc1 gene inactivation at 2 weeks of age was sufficient to cause astrogliosis and mild epilepsy in Tsc1<sup>GFAP</sup><sup>-Cre</sup><sup>ER</sup> mice, but the phenotype was much less severe than that observed with prenatal Tsc1 gene inactivation in Tsc1<sup>GFAP</sup><sup>-Cre</sup> mice. 29023667 2017
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.400 Biomarker disease BEFREE The aim of this study was to investigate the distribution of GFAP Delta164/Deltaexon 6 expressing cells, in focal lesions associated with chronic intractable epilepsy, in light of the increasing interest in the role of specific astrocyte subtypes in epilepsy. 20430588 2010
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.400 Biomarker disease CTD_human [Astrocytic gap junction in the hippocampus of rats with lithium pilocarpine-induced epilepsy]. 21177194 2010
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.400 Biomarker disease BEFREE Primary astrocytes were isolated and cultured from seven epilepsy brain resections and astrocyte purity was defined by GFAP reactivity. 17535102 2007
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.400 AlteredExpression disease BEFREE Surprisingly, immunohistochemical experiments using a polyclonal antiexcitatory amino acid transporter 2 antibody, showed a different localization of this protein in epilepsy derived tissue as compared to post mortem controls although glial markers such as glial fibrillary acidic protein and glutamine synthase showed similar patterns of staining. 10336123 1999