Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
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0.550 | AlteredExpression | disease | BEFREE | The protective role of Foxp3 in crescentic GN was associated with a markedly suppressed expression of proinflammatory interleukin-1 beta (IL-1β), tumour necrosis factor-alpha (TNF-α) and monocyte chemoattractant protein 1 (MCP-1), and diminished infiltration of the kidneys by CD3<sup>+</sup> T cells and F4/80<sup>+</sup> macrophages. | 28469165 | 2017 | ||||
|
0.550 | Biomarker | disease | BEFREE | TLR3 expression correlated positively with HCV viral load, interleukin-1β, serum creatinine and inversely with creatinine clearance in patients with HCV-positive glomerulonephritis. | 21623661 | 2011 | ||||
|
0.550 | Biomarker | disease | RGD | Renoprotective effect of rosuvastatin in DOCA-salt hypertensive rats. | 19948880 | 2010 | ||||
|
0.550 | Biomarker | disease | CTD_human | Cytokines and T-cell responses in superantigen-related glomerulonephritis following methicillin-resistant Staphylococcus aureus infection. | 10910440 | 2000 | ||||
|
0.550 | Biomarker | disease | BEFREE | To address whether these two diseases have a common genetic background, the polymorphism of the variable number tandem repeat (VNTR) of IL-1 receptor antagonist (IL-1ra) gene has been analyzed using PCR in patients diagnosed with HSPN (N = 43) and IgAN (N = 97), together with normal controls (N = 98) and patients with acute post-infectious glomerulonephritis (APGN), under the concept that IL-1 might play an important role in mediating pathogenesis of vasculitis and glomerulonephritis. | 9186886 | 1997 | ||||
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0.550 | Biomarker | disease | CTD_human | A case of superantigen-related glomerulonephritis after methicillin-resistant Staphylococcus aureus (MRSA) infection. | 9403216 | 1997 | ||||
|
0.550 | AlteredExpression | disease | BEFREE | In segmental sclerosing lesions in FSGS and in IgA-GN with marked glomerular proliferation and/or sclerosis, a reduced expression of the PP-44 antigen and a diminished ability of podocytes to produce IL-1/IL-1 related peptides are noted. | 9263995 | 1997 | ||||
|
0.550 | Biomarker | disease | BEFREE | In situ production of TNF-alpha, IL-1 beta and IL-2R in ANCA-positive glomerulonephritis. | 8455368 | 1993 |