Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2660
Gene Symbol: MSTN
MSTN
0.570 AlteredExpression disease BEFREE Serum myostatin levels were higher in CHF patients than in controls. 31056368 2019
Entrez Id: 2660
Gene Symbol: MSTN
MSTN
0.570 AlteredExpression disease BEFREE Although there are disparities in pathophysiology and epidemiology between male and female patients with HF, it remains unclear whether there is gender difference in myostatin expression and whether it is associated with weight loss in HF patients. 28465115 2017
Entrez Id: 2660
Gene Symbol: MSTN
MSTN
0.570 AlteredExpression disease BEFREE Myostatin expression is also found in heart in a much less extent, but it can be upregulated in pathological conditions, such as heart failure. 29069231 2017
Entrez Id: 2660
Gene Symbol: MSTN
MSTN
0.570 Biomarker disease BEFREE Circulating and local myostatin is elevated in chronic heart failure and poses a major player in cardiac cachexia. 24680839 2014
Entrez Id: 2660
Gene Symbol: MSTN
MSTN
0.570 AlteredExpression disease BEFREE In late-stage CHF, exercise training led to a 36% reduction of the mRNA and a 23% decrease of the myostatin protein compared to baseline. 21450574 2012
Entrez Id: 2660
Gene Symbol: MSTN
MSTN
0.570 Biomarker disease BEFREE We describe the development of the first ELISA for myostatin immunoreactivity and its validation during recompensating therapy for CHF. 22561185 2012
Entrez Id: 2660
Gene Symbol: MSTN
MSTN
0.570 Biomarker disease BEFREE To therapeutically influence skeletal muscle wasting, direct inhibition of myostatin was shown to positively impact skeletal muscle mass in heart failure, suggesting a promising strategy for the treatment of cardiac cachexia in the future. 21421824 2011
Entrez Id: 2660
Gene Symbol: MSTN
MSTN
0.570 Biomarker disease CTD_human However, the expression of myostatin in chronic heart failure resulting from volume-overload and after treatment with beta-blockers is little known. 16968467 2006
Entrez Id: 2660
Gene Symbol: MSTN
MSTN
0.570 Biomarker disease RGD However, the expression of myostatin in chronic heart failure resulting from volume-overload and after treatment with beta-blockers is little known. 16968467 2006