Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
0.010 AlteredExpression disease BEFREE Together, these results suggest that upregulation of GDF15, downregulation of FT and FT/E2 ratio may be involved in the outcome of HBV infection and the severity of HCC. 31766097 2020
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.010 Biomarker disease BEFREE A prognostic prediction model, NRISK4 = (-0.333 × [CDH1] - 0.400 × [ID2] + 0.339 × [MMP9] + 0.387 × [TCF3]) was constructed, but from patients with HCC with predominantly hepatitis B virus infection. 31421377 2020
Entrez Id: 406977
Gene Symbol: MIR199A2
MIR199A2
0.010 Biomarker disease BEFREE In this study, we provide evidence linking the coexistence of hepatitis B virus X protein (HBx) and transforming growth factor beta 1 (TGF-β1) with miR-199a-3p in the malignant transformation of HPCs. 31740785 2020
Entrez Id: 6559
Gene Symbol: SLC12A3
SLC12A3
0.010 Biomarker disease BEFREE Novel fluoronucleoside analog NCC inhibits lamivudine-resistant hepatitis B virus in a hepatocyte model. 30586543 2020
Entrez Id: 8027
Gene Symbol: STAM
STAM
0.010 Biomarker disease BEFREE Suppression of EGFR ubiquitination by site-directed mutagenesis or by knocking down two EGFR-sorting molecules, signal-transducing adaptor molecule (STAM) and lysosomal protein transmembrane 4 β (LAPTM4B), suggested that EGFR transport to the late endosome is critical for efficient HBV infection. 31836663 2020
Entrez Id: 5563
Gene Symbol: PRKAA2
PRKAA2
0.010 Biomarker disease BEFREE AMPK and Akt/mTOR signalling pathways participate in glucose-mediated regulation of hepatitis B virus replication and cellular autophagy. 31746509 2020
Entrez Id: 8061
Gene Symbol: FOSL1
FOSL1
0.010 AlteredExpression disease BEFREE High expression of FOSL1 was significantly associated with larger tumor size (P = 0.021), hepatitis B virus infection (P = 0.014), advanced T stage (P = 0.014), and tumor necrosis metastasis stage (P = 0.014). 31274473 2020
Entrez Id: 3161
Gene Symbol: HMMR
HMMR
0.010 Biomarker disease BEFREE Hepatitis B virus X protein induces RHAMM-dependent motility in hepatocellular carcinoma cells via PI3K-Akt-Oct-1 signaling. 31792079 2020
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
0.010 Biomarker disease BEFREE Serum YKL-40 was significantly increased in CPH patients, and was associated with Child-Pugh score and HBV infection. 31427175 2020
Entrez Id: 406976
Gene Symbol: MIR199A1
MIR199A1
0.010 Biomarker disease BEFREE In this study, we provide evidence linking the coexistence of hepatitis B virus X protein (HBx) and transforming growth factor beta 1 (TGF-β1) with miR-199a-3p in the malignant transformation of HPCs. 31740785 2020
Entrez Id: 101929111
Gene Symbol: LINC01149
LINC01149
0.010 AlteredExpression disease BEFREE LINC01149 variant modulates MICA expression that facilitates hepatitis B virus spontaneous recovery but increases hepatocellular carcinoma risk. 31754211 2020
Entrez Id: 824
Gene Symbol: CAPN2
CAPN2
0.010 Biomarker disease BEFREE CAPN2 acts as an indicator of hepatitis B virus to induce hepatic fibrosis. 31680308 2020
Entrez Id: 5564
Gene Symbol: PRKAB1
PRKAB1
0.010 Biomarker disease BEFREE AMPK and Akt/mTOR signalling pathways participate in glucose-mediated regulation of hepatitis B virus replication and cellular autophagy. 31746509 2020
Entrez Id: 483
Gene Symbol: ATP1B3
ATP1B3
0.010 AlteredExpression disease BEFREE Here, we demonstrated that ATP1B3 overexpression reduced the quantity of hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) in supernatants of HBV expression plasmids cotransfected HepG2 cells. 31556466 2020
Entrez Id: 5004
Gene Symbol: ORM1
ORM1
0.010 Biomarker disease BEFREE Urine alpha-fetoprotein and orosomucoid 1 as biomarkers of hepatitis B virus-associated hepatocellular carcinoma. 31736338 2020
Entrez Id: 1268
Gene Symbol: CNR1
CNR1
0.010 AlteredExpression disease BEFREE Here, we demonstrate that a global knockout of the cannabinoid receptor 1 gene (CB1<sup>-/-</sup>) reduced the expression of the lipid droplet binding protein PLIN2 in the livers of CB1<sup>-/-</sup> and hepatitis B surface protein (HBs)-transgenic mice, which spontaneously develop hepatic steatosis. 31570772 2020
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
0.010 Biomarker disease BEFREE Levels of serum sE-cadherin, total antioxidant capacity (TAC), glutathione (GSH), superoxide dismutase (SOD), total oxidant activity (TOA), NADPH oxidase 2 (NOX2), and malondialdehyde (MDA), from 51 patients with hepatitis B envelope antigen (HBeAg)-negative CHB, 54 patients with HBeAg-positive CHB, and 109 healthy individuals were detected by enzyme-linked immunosorbent assay. 31429942 2020
Entrez Id: 123
Gene Symbol: PLIN2
PLIN2
0.010 Biomarker disease BEFREE Here, we demonstrate that a global knockout of the cannabinoid receptor 1 gene (CB1<sup>-/-</sup>) reduced the expression of the lipid droplet binding protein PLIN2 in the livers of CB1<sup>-/-</sup> and hepatitis B surface protein (HBs)-transgenic mice, which spontaneously develop hepatic steatosis. 31570772 2020
Entrez Id: 450095
Gene Symbol: PLF
PLF
0.010 GeneticVariation disease BEFREE Chronic Hepatitis B Infection in Children and Its Relation to Pulmonary Function Tests: A Case-Control Study. 31764377 2020
Entrez Id: 55511
Gene Symbol: SAGE1
SAGE1
0.010 Biomarker disease BEFREE With the target set at 90% coverage of birth-dose hepatitis B vaccine by 2030, it is imperative to immediately incorporate WHO/SAGE recommendations of administering the hepatitis B vaccine birth dose until 7 d into the National Immunization Schedule (NIS). 31295047 2020
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
0.010 Biomarker disease BEFREE Diagnostic value of LncRNA-MEG3 as a serum biomarker in patients with hepatitis B complicated with liver fibrosis. 31173310 2019
Entrez Id: 2205
Gene Symbol: FCER1A
FCER1A
0.010 GeneticVariation disease BEFREE In gene-by-gene analyses, one gene, FCER1A (rs7549785), reached genome-wide significance (P = 2.65 × 10<sup>-8</sup> ) in East Asian patients for hepatitis B surface antigen (HBsAg) clearance, with a moderate effect size (odds ratio = 4.74). 30972912 2019
Entrez Id: 10559
Gene Symbol: SLC35A1
SLC35A1
0.010 Biomarker disease BEFREE The present study aimed to investigate the clinical significance and prospective molecular mechanism of cystatin (CST) genes in patients with hepatitis B virus (HBV)‑related hepatocellular carcinoma (HCC). 31115549 2019
Entrez Id: 8611
Gene Symbol: PLPP1
PLPP1
0.010 AlteredExpression disease BEFREE We further evaluated the enzyme levels of PC pathways and found that PCYT1A and LPP1 for PC synthesis were up-regulated after HBV infection. 31506451 2019
Entrez Id: 23547
Gene Symbol: LILRA4
LILRA4
0.010 AlteredExpression disease BEFREE Increased expression of BDCA-2, ILT7 and TLR-9 mRNA was negatively correlated with HBV DNA (P<0.05). 31798696 2019