Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6348
Gene Symbol: CCL3
CCL3
0.340 Biomarker group BEFREE Twelve selected cytokines, including 9 inflammatory cytokines and chemokines (interleukin [IL]-1α, IL-1β, IL-6, tumor necrosis factor-α, IL-8, interferon-γ inducible protein-10 [IP-10], monocyte chemoattractant protein-1, macrophage inflammatory protein [MIP]-1α, MIP-1β), hematopoietic IL-7, and granulocyte macrophage colony-stimulating factor, and regulatory IL-10 were measured prior to HIV infection in cervicovaginal lavages from 58 HIV seroconverters and 58 matched uninfected controls and in plasma from a subset of 107 of these women from the Centre for the AIDS Programme of Research in South Africa 004 tenofovir gel trial. 25900168 2015
Entrez Id: 6348
Gene Symbol: CCL3
CCL3
0.340 AlteredExpression group BEFREE A decline in CCL3-5 chemokine gene expression during primary simian-human immunodeficiency virus infection. 17684570 2007
Entrez Id: 6348
Gene Symbol: CCL3
CCL3
0.340 Biomarker group LHGDN These data indicate that lymphocytes of HIV patients display a disrupted capacity to secrete the beta-chemokines MIP-1 alpha and MIP-1 beta, which may constitute a mechanism of immune dysfunction in progressive HIV infection. 15585099 2004
Entrez Id: 6348
Gene Symbol: CCL3
CCL3
0.340 AlteredExpression group BEFREE As MIP-1 alpha and MIP-1 beta are potent chemoattractants for both monocytes and specific subpopulations of lymphocytes, this dysregulation of beta chemokine expression may influence the trafficking of leukocytes during HIV infection. 8570619 1996
Entrez Id: 6348
Gene Symbol: CCL3
CCL3
0.340 Biomarker group CTD_human