Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.250 Biomarker disease BEFREE The aims of this study were to determine the levels of leptin, C-reactive protein (CRP), and ferritin in relation to volume status and to assess the relationship between leptin and volume and inflammatory status in chronic HD patients. 30225886 2019
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.250 Biomarker disease BEFREE Multivariable logistic regression analysis showed that leptin (odds ratio [OR] 1.09; 95% confidence interval [CI] 1.04-1.14; p <0.001), diabetes (OR 7.17; CI 1.39-37.00; p = 0.019), body fat mass (OR 1.16; CI 1.02-1.33; p = 0.027); and hemoglobin (OR 2.11; CI 1.15-3.87; p = 0.015) were independently associated with arterial stiffness in HD patients. 29304064 2018
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.250 AlteredExpression disease BEFREE Leptin levels and fat-free mass measurements using bioelectric impedance analysis may be good screening tools to identify HD patients at risk for weight loss. 25904208 2015
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.250 Biomarker disease BEFREE Leptin secretion rate increases with higher CAG repeat number in Huntington's disease patients. 19548952 2010
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.250 Biomarker disease RGD Increased numbers of motor activity peaks during light cycle are associated with reductions in adrenergic alpha(2)-receptor levels in a transgenic Huntington's disease rat model. 19573560 2009
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.250 AlteredExpression disease LHGDN Circulating and cerebrospinal fluid ghrelin and leptin: potential role in altered body weight in Huntington's disease. 15476444 2004