Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1910
Gene Symbol: EDNRB
EDNRB
0.500 Biomarker phenotype RGD The aldose reductase inhibitors sorbinil and zopolrestat mitigated endotoxin-induced pulmonary hypertension, ET-1 stimulation, and differential ET(B) receptor regulation. 18091567 2008
Entrez Id: 1910
Gene Symbol: EDNRB
EDNRB
0.500 Biomarker phenotype CTD_human Development of occlusive neointimal lesions in distal pulmonary arteries of endothelin B receptor-deficient rats: a new model of severe pulmonary arterial hypertension. 15927975 2005
Entrez Id: 1910
Gene Symbol: EDNRB
EDNRB
0.500 Biomarker phenotype RGD Thus, an exaggerated response to MCT during ETB receptor blockade also seems to be mediated by ETA receptor activation, thereby suggesting that ETA receptor-mediated action is exclusively contributive to the pathogenesis of MCT-induced pulmonary hypertension, although we cannot rule out a protective role of ETB receptor-mediated action. 15243299 2004