| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.300 | Biomarker | phenotype | CTD_human | Intravenous injection of artemetin (0.75 mg/kg) significantly reduced the hypertensive response to angiotensin I while increased the average length of bradykinin-induced hypotension.Artemetin (1.5 mg/kg, p.o.) was also able to reduce plasma (about 37%) and vascular (up to 63%) ACE activity in vitro, compared to control group. | 21420289 | 2011 | ||||
|
0.300 | Biomarker | phenotype | CTD_human | In the presence of lisinopril (ACE inhibitor), but not candoxatril (NEP inhibitor) or apstatin (APP inhibitor), bradykinin also elicited hypotension. | 18084312 | 2008 | ||||
|
0.300 | Biomarker | phenotype | CTD_human | This study tests the primary hypothesis that blocking the bradykinin B(2) receptor would attenuate protamine-related hypotension. | 16321614 | 2005 | ||||
|
0.300 | Biomarker | phenotype | CTD_human | The magnitude of BK-induced hypotension was significantly attenuated in all rats treated with Hoe 140.4. | 14744816 | 2004 | ||||
|
0.300 | Biomarker | phenotype | CTD_human | The hypotension response to acetylcholine and bradykinin studied in anesthetized NO-compromised rats, was unexpectedly enhanced. | 10805402 | 2000 | ||||
|
0.300 | Biomarker | phenotype | CTD_human | Signalling pathways in bradykinin- and nitric oxide-induced hypotension in the normotensive rat; role of K+-channels. | 9249246 | 1997 | ||||
|
0.300 | Biomarker | phenotype | CTD_human | Influence of a kinin antagonist on acute hypotensive responses induced by bradykinin and captopril in spontaneously hypertensive rats. | 1334354 | 1992 | ||||
|
0.300 | Biomarker | phenotype | CTD_human | The present results support the hypothesis that immediate hypotension induced by captopril involves a prostaglandin-dependent component possibly resulting from increased bradykinin levels generated in the vicinity of captopril action. | 2404862 | 1990 | ||||
|
0.300 | Biomarker | phenotype | CTD_human | Examinations on contribution of bradykinin in the action of dopamine in circulatory system of rats. I. Influence of bradykinin in the action of dopamine on arterial blood pressure of rats. | 6675575 | 1983 |