Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.350 | GeneticVariation | group | GWASCAT | Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. | 26192919 | 2015 | ||||
|
0.350 | Biomarker | group | BEFREE | Our results supporting IL2RA and IL2RB as promising candidate genes for IBD and suggesting a potential role of IL2R in the pathogenesis of IBD, likely involves regulatory T cells. | 23972291 | 2013 | ||||
|
0.350 | GeneticVariation | group | GWASCAT | Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. | 23128233 | 2012 | ||||
|
0.350 | GeneticVariation | group | GWASDB | Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. | 23128233 | 2012 | ||||
|
0.350 | AlteredExpression | group | BEFREE | The downregulation of TRF2 and RAP1 mRNA expression in CD25+ T-lymphocytes in IBD suggests that these telomere binding proteins play a role in telomere regulation and may contribute to the telomeric fusions and chromosomal abnormalities observed in UC. | 20061197 | 2010 | ||||
|
0.350 | Biomarker | group | BEFREE | Therefore, we decide to investigate the association of polymorphisms in the IL-2 axis (IL2, IL2RA, and IL2RB genes) with inflammatory bowel diseases (IBDs). | 19471255 | 2009 | ||||
|
0.350 | Biomarker | group | BEFREE | Intestinal homeostasis and maintenance of tolerance to harmless antigens in the intestine has been shown to be maintained by CD4+ CD25+ T regulatory cells (Treg) in animal models of inflammatory bowel diseases. | 18422560 | 2008 | ||||
|
0.350 | AlteredExpression | group | BEFREE | Interestingly, LP CD4(+)CD25(bright) T cells with regulatory T activity were significantly increased in patients with active inflammatory bowel disease. | 15322172 | 2004 | ||||
|
0.350 | Biomarker | group | MGD |