Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10636
Gene Symbol: RGS14
RGS14
0.140 GeneticVariation disease BEFREE In addition, subjects carrying the minor AA genotype at rs12654812 (regulator of G protein signaling 14 (RGS14)) have higher susceptibility to nephrolithiasis (OR = 1.91, p = 0.0017). 31754202 2019
Entrez Id: 10636
Gene Symbol: RGS14
RGS14
0.140 GeneticVariation disease BEFREE Our results suggest that the RGS14 polymorphism is involved in the etiology of nephrolithiasis and thus may be a genetic marker for nephrolithiasis. 29577426 2018
Entrez Id: 10636
Gene Symbol: RGS14
RGS14
0.140 GeneticVariation disease GWASCAT Common and rare variants associated with kidney stones and biochemical traits. 26272126 2015
Entrez Id: 10636
Gene Symbol: RGS14
RGS14
0.140 GeneticVariation disease BEFREE We selected seven single-nucleotide polymorphisms (SNPs): rs12654812 and rs11746443 from 5q35.3 (RGS14-SLC34A1-PFN3-F12); rs12669187 and rs1000597 from 7p14.3 (INMT-FAM188B-AQP1); and rs7981733, rs1170155, and rs4142110 from 13q14.1 (DGKH (diacylglycerol kinase)), which were previously reported to be significantly associated with nephrolithiasis. rs12654812, rs12669187 and rs7981733 were significantly associated with nephrolithiasis after Bonferroni's correction (P=3.12 × 10(-3), odds ratio (OR)=1.43; P=6.40 × 10(-3), OR=1.57; and P=5.00 × 10(-3), OR=1.41, respectively). 23719187 2013
Entrez Id: 10636
Gene Symbol: RGS14
RGS14
0.140 GeneticVariation disease BEFREE Here we found three novel loci for nephrolithiasis: RGS14-SLC34A1-PFN3-F12 on 5q35.3 (rs11746443; P = 8.51×10⁻¹², odds ratio (OR) = 1.19), INMT-FAM188B-AQP1 on 7p14.3 (rs1000597; P = 2.16×10⁻¹⁴, OR = 1.22), and DGKH on 13q14.1 (rs4142110; P = 4.62×10⁻⁹, OR = 1.14). 22396660 2012