Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group BEFREE Moreover, it is shown that 1.7 times increase in urine NGAL after angiography is a valuable cut off point for clinicians to discriminate high risk patients for contrast nephropathy. 31209192 2019
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group BEFREE This study aimed to compare the levels of plasma neutrophil gelatinase-associated lipocalin (NGAL), matrix metalloproteinase (MMP)-9, high-sensitivity C-reactive protein (hs-CRP), and interleukin (IL)-1β across different clinical presentations of coronary artery disease and to evaluate the relationship between those biomarkers and the severity of coronary artery lesions in patients without kidney disease. 31387110 2019
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group BEFREE NGAL levels were measured via enzyme-linked immunosorbent assays, as were those of three additional urinary biomarkers for kidney diseases: Monocyte chemotactic protein-1 (MCP-1), liver-type fatty acid-binding protein (L-FABP), and human epididymis secretory protein 4 (HE4). 31242630 2019
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group BEFREE Secondary outcomes included the following: 1) acute kidney injury according to the serum creatinine criteria of the Kidney Diseases: Improving Global Outcomes; 2) acute kidney injury with serum creatinine corrected for fluid balance; 3) plasma neutrophil gelatinase-associated lipocalin; 4) cystatin C; 5) urea; 6) lactate; 7) hemodynamic variables; 8) use of diuretics in the PICU; 9) need of dialysis; 10) length of ventilator therapy; and 11) length of PICU stays. 31274775 2019
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group BEFREE Cystatin C (Cyst C) and neutrophil gelatinase-associated lipocalin (NGAL) are novel biomarkers for the earlier detection of latent kidney disease. 29946947 2019
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group BEFREE An enzyme-free electrochemical immunoassay is described for the neutrophil gelatinase-associated lipocalin (NGAL; a biomarker of kidney disease). 29896648 2018
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group BEFREE Serum NGAL showed an early association with VL-associated nephropathy and may be used to improve clinical management strategies and decrease morbimortality in VL patients. 29987885 2018
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group BEFREE Widely available markers, serum cystatin C, urine IgG, transferrin, and NGAL, may help in early assessment of kidney disease in T2DM patients; however, large prospective studies are needed to confirm the conclusion. 30158836 2018
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group BEFREE Indeed, numerous studies have demonstrated a role for NGAL in both cardiovascular and renal diseases. 29739822 2018
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group BEFREE This study was aimed to investigate the efficacy of matrix metalloproteinase-9 (MMP-9), tissue inhibitor of metalloproteinase-1 (TIMP-1), and the neutrophil gelatinase-associated lipocalin (NGAL)-bound form of MMP-9 (MMP-9/NGAL complex) markers in the determination of early nephropathy in patients with type 2 diabetes mellitus. 30367022 2018
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group BEFREE Urinary RBP and NGAL Levels are Associated with Nephropathy in Patients with Type 2 Diabetes. 28954270 2017
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group BEFREE We used natural log-transformed NGAL in a logistic regression model to predict stage 2/3 AKI (defined by Kidney Disease International Global Organization). 28698338 2017
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group CTD_human Rat Urinary Osteopontin and Neutrophil Gelatinase-Associated Lipocalin Improve Certainty of Detecting Drug-Induced Kidney Injury. 27026710 2016
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group BEFREE In four annual serial urine samples collected from 107 patients with ADPKD in the Consortium for Radiologic Imaging for the Study of Polycystic Kidney Disease (CRISP) study, NGAL and IL-18 excretion rates were determined in conjunction with measures of total kidney volume and estimated glomerular filtration rate (eGFR) by the Modification of Diet in Renal Disease equation. 22258321 2012
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group BEFREE NGAL-Siderocalin in kidney disease. 22728330 2012
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group CTD_human Transcriptional analysis of kidneys during repair from AKI reveals possible roles for NGAL and KIM-1 as biomarkers of AKI-to-CKD transition. 20181666 2010
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group CTD_human Evaluation of the usefulness of urinary biomarkers for nephrotoxicity in rats. 20438795 2010
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 AlteredExpression group LHGDN Elevated urine neutrophil gelatinase-associated lipocalin can diagnose acute kidney injury in patients with chronic kidney diseases. 19092815 2009
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group CTD_human Comparative analysis of novel noninvasive renal biomarkers and metabonomic changes in a rat model of gentamicin nephrotoxicity. 19349640 2009
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group LHGDN Plasma neutrophil gelatinase-associated lipocalin predicts acute kidney injury, morbidity and mortality after pediatric cardiac surgery: a prospective uncontrolled cohort study. 18070344 2007
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
0.400 Biomarker group BEFREE Here, we review the expression, siderophore-dependent biological activities and clinical significance of NGAL in epithelial development and in kidney disease. 16775460 2006