Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
0.330 AlteredExpression disease BEFREE The results showed a significant rise in creatinine, urea, and cystatin C (cys C) levels and upregulation of p38 mRNA, whereas a significant decline in NAD(P)H quinone oxidoreductase 1 (NQO-1) protein and downregulation of B-cell lymphoma-2 (Bcl-2) mRNA and vascular endothelial growth factor (VEGF) mRNA were recorded in AKI. 30976980 2019
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
0.330 Biomarker disease BEFREE These findings suggest that NQO1 deletion might be associated with decreased MRN complex expression, which might be partially responsible for the exacerbation of cisplatin-induced AKI in the absence of NQO1. 26723870 2016
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
0.330 Biomarker disease BEFREE In vivo, NQO1-KO mice displayed a significant increase in cisplatin-induced acute kidney injury (AKI), as indicated by elevated tubular damage and apoptosis as well as by suppressed cytoprotective signals. 26935540 2016
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
0.330 Biomarker disease CTD_human These findings suggest that NQO1 deletion might be associated with decreased MRN complex expression, which might be partially responsible for the exacerbation of cisplatin-induced AKI in the absence of NQO1. 26723870 2016