Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 567
Gene Symbol: B2M
B2M
0.350 Biomarker disease BEFREE It is unclear, however, if levels of β2-microglobulin and serum creatinine were lower for other reasons, such as if any patients with AKI required dialysis.This work provides an important addition to the field of AKI research, specifically in the evaluation of readily measurable biomarkers and outcomes after AKI. 31345164 2019
Entrez Id: 567
Gene Symbol: B2M
B2M
0.350 Biomarker disease BEFREE Median levels of 5 biomarkers were significantly higher in AKI cases than controls at 1-3 days before AKI onset (all µg/mmol): clusterin [58(8-411) versus 7(3-17)], beta-2-microglobulin [1632(913-3823) versus 253(61-791)], KIM1 [0.16(0.13-0.76) versus 0.07(0.05-0.15)], MCP1 [0.40(0.16-1.90) versus 0.07(0.04-0.17)], and cystatin-C [33(27-2990) versus 11(7-19)], all p<0.05; their AUROC for AKI prediction were >0.80 (confidence intervals >0.50), with average accuracy highest for clusterin (86%), followed by beta-2-microglobulin, cystatin-C, MCP1, and KIM1 (57%) after cross-validation. 31296157 2019
Entrez Id: 567
Gene Symbol: B2M
B2M
0.350 Biomarker disease BEFREE The persistence of high concentrations of beta-2-microglobulin (β2M) in the blood of patients with acute renal failure leads to the development of the dialysis-related amyloidosis. 30223436 2018
Entrez Id: 567
Gene Symbol: B2M
B2M
0.350 AlteredExpression disease BEFREE However, neither uB2M nor sB2M levels associated with recovery from AKI. 30524714 2018
Entrez Id: 567
Gene Symbol: B2M
B2M
0.350 AlteredExpression disease BEFREE The baseline β2-microglobulin level was the strongest predictor of acute kidney injury as a complication of transcatheter aortic valve replacement [odds ratio (OR) 5.277, P = 0.009]. 28962501 2017
Entrez Id: 567
Gene Symbol: B2M
B2M
0.350 Biomarker disease CTD_human A Multiplatform Approach for the Discovery of Novel Drug-Induced Kidney Injury Biomarkers. 28885000 2017
Entrez Id: 567
Gene Symbol: B2M
B2M
0.350 Biomarker disease CTD_human Decrease in urinary creatinine in acute kidney injury influences diagnostic value of urinary biomarker-to-creatinine ratio in rats. 22005293 2011
Entrez Id: 567
Gene Symbol: B2M
B2M
0.350 Biomarker disease CTD_human The effects of diltiazem on methotrexate-induced nephrotoxicity. 2689182 1989