Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker group CTD_human Virgin coconut oil (VCO) by normalizing NLRP3 inflammasome showed potential neuroprotective effects in Amyloid-β induced toxicity and high-fat diet fed rat. 29729307 2018
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		0.300 Biomarker group CTD_human Role of TLR4 in olfactory-based spatial learning activity of neonatal mice after developmental exposure to diesel exhaust origin secondary organic aerosol. 29107071 2017
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker group CTD_human [Gly14]-Humanin Protects Against Amyloid β Peptide-Induced Impairment of Spatial Learning and Memory in Rats. 27306655 2016
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker group CTD_human Ethosuximide Induces Hippocampal Neurogenesis and Reverses Cognitive Deficits in an Amyloid-β Toxin-induced Alzheimer Rat Model via the Phosphatidylinositol 3-Kinase (PI3K)/Akt/Wnt/β-Catenin Pathway. 26420483 2015
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		0.300 Therapeutic group CTD_human IL-1 receptor antagonist attenuates neonatal lipopolysaccharide-induced long-lasting learning impairment and hippocampal injury in adult rats. 25665855 2015
Entrez Id: 79823
Gene Symbol: CAMKMT
CAMKMT 		0.300 Biomarker group CTD_human Calmodulin Methyltransferase Is Required for Growth, Muscle Strength, Somatosensory Development and Brain Function. 26247364 2015
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker group CTD_human Notoginsenoside R1 increases neuronal excitability and ameliorates synaptic and memory dysfunction following amyloid elevation. 25213453 2014
Entrez Id: 9365
Gene Symbol: KL
KL 		0.300 Biomarker group CTD_human Growth Hormone-Releaser Diet Attenuates Cognitive Dysfunction in Klotho Mutant Mice via Insulin-Like Growth Factor-1 Receptor Activation in a Genetic Aging Model. 25309793 2014
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.300 Biomarker group CTD_human Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity. 24556215 2014
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		0.300 Biomarker group CTD_human Notoginsenoside R1 increases neuronal excitability and ameliorates synaptic and memory dysfunction following amyloid elevation. 25213453 2014
Entrez Id: 10367
Gene Symbol: MICU1
MICU1 		0.300 Biomarker group CTD_human Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling. 24336167 2014
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker group CTD_human Protective effects of astragalosides on dexamethasone and Aβ25-35 induced learning and memory impairments due to decrease amyloid precursor protein expression in 12-month male rats. 22484447 2012
Entrez Id: 5447
Gene Symbol: POR
POR 		0.300 Biomarker group CTD_human PAH particles perturb prenatal processes and phenotypes: protection from deficits in object discrimination afforded by dampening of brain oxidoreductase following in utero exposure to inhaled benzo(a)pyrene. 21987461 2012
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.300 Biomarker group CTD_human A proteomic analysis of MCLR-induced neurotoxicity: implications for Alzheimer's disease. 22430071 2012
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7 		0.300 Biomarker group CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146 2011
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.300 Biomarker group CTD_human Involvement of interleukin-1 in lipopolysaccaride-induced microglial activation and learning and memory deficits. 21290410 2011
Entrez Id: 57084
Gene Symbol: SLC17A6
SLC17A6 		0.300 Biomarker group CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146 2011
Entrez Id: 6855
Gene Symbol: SYP
SYP 		0.300 Biomarker group CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146 2011
Entrez Id: 3363
Gene Symbol: HTR7
HTR7 		0.300 Biomarker group CTD_human Optimization of (arylpiperazinylbutyl)oxindoles exhibiting selective 5-HT₇ receptor antagonist activity. 21859099 2011
Entrez Id: 4204
Gene Symbol: MECP2
MECP2 		0.300 Biomarker group CTD_human Novel variants identified in methyl-CpG-binding domain genes in autistic individuals. 19921286 2010
Entrez Id: 4763
Gene Symbol: NF1
NF1 		0.300 Biomarker group CTD_human ALTERED CALCIUM CURRENTS AND AXONAL GROWTH IN Nf1 HAPLOINSUFFICIENT MICE. 21949590 2010
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.300 Therapeutic group CTD_human Vascular endothelial growth factor attenuates status epilepticus-induced behavioral impairments in rats. 20801723 2010
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker group CTD_human Atorvastatin prevents hippocampal cell death, neuroinflammation and oxidative stress following amyloid-β(1-40) administration in mice: evidence for dissociation between cognitive deficits and neuronal damage. 20816828 2010
Entrez Id: 43
Gene Symbol: ACHE
ACHE 		0.300 Biomarker group CTD_human Hyposensitivity to the amnesic effects of scopolamine or amyloid beta(25-35) peptide in heterozygous acetylcholinesterase knockout (AChE(+/-)) mice. 18533140 2008
Entrez Id: 347
Gene Symbol: APOD
APOD 		0.300 Biomarker group CTD_human Apolipoprotein D is involved in the mechanisms regulating protection from oxidative stress. 18419796 2008