Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 286530
Gene Symbol: P2RY8
P2RY8
0.340 Biomarker disease BEFREE Genomic and transcriptional landscape of P2RY8-CRLF2-positive childhood acute lymphoblastic leukemia. 27899802 2017
Entrez Id: 286530
Gene Symbol: P2RY8
P2RY8
0.340 GeneticVariation disease BEFREE As controversy exists regarding the prognostic significance of genomic rearrangements of CRLF2 in pediatric B-precursor acute lymphoblastic leukemia (ALL) classified as standard/intermediate-risk (SR) or high-risk (HR), we assessed the prognostic significance of CRLF2 mRNA expression, CRLF2 genomic lesions (IGH@-CRLF2, P2RY8-CRLF2, CRLF2 F232C), deletion/mutation in genes frequently associated with high CRLF2 expression (IKZF1, JAK, IL7R), and minimal residual disease (MRD) in 1061 pediatric ALL patients (499 HR and 562 SR) on COG Trials P9905/P9906. 22368272 2012
Entrez Id: 286530
Gene Symbol: P2RY8
P2RY8
0.340 AlteredExpression disease BEFREE To investigate whether and to what extent different clone sizes influence disease and relapse development, we quantified the genomic P2RY8-CRLF2 fusion product and correlated it with the corresponding CRLF2 expression levels in patients enrolled in the BFM-ALL 2000 protocol in Austria. 23091296 2012
Entrez Id: 286530
Gene Symbol: P2RY8
P2RY8
0.340 Biomarker disease CTD_human We identified the P2RY8-CRLF2 fusion in 7% of individuals with B-progenitor ALL and 53% of individuals with ALL associated with Down syndrome. 19838194 2009
Entrez Id: 286530
Gene Symbol: P2RY8
P2RY8
0.340 GeneticVariation disease BEFREE We identified the P2RY8-CRLF2 fusion in 7% of individuals with B-progenitor ALL and 53% of individuals with ALL associated with Down syndrome. 19838194 2009