Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
0.050 GeneticVariation disease BEFREE First: This is the first report on CMML with double-mutations of DNMT3A and FLT3-ITD. 28102729 2017
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
0.050 Biomarker disease BEFREE We genotyped ASXL1 and up to 18 other genes including epigenetic (TET2, EZH2, IDH1, IDH2, DNMT3A), splicing (SF3B1, SRSF2, ZRSF2, U2AF1), transcription (RUNX1, NPM1, TP53), and signaling (NRAS, KRAS, CBL, JAK2, FLT3) regulators in 312 patients with CMML. 23690417 2013
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
0.050 GeneticVariation disease BEFREE FLT3 mutations were identified in 13 (4.3%) CMML patients: 8 had FLT3-ITD mutation and 5 had FLT3-TKD mutation. 23115106 2013
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
0.050 GeneticVariation disease BEFREE FLT3 mutations confer enhanced proliferation and survival properties to multipotent progenitors in a murine model of chronic myelomonocytic leukemia. 17936561 2007
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
0.050 GeneticVariation disease BEFREE Five patients (2.5%)--2 of the 99 patients who had refractory anemia with excess blasts and 3 of the 51 patients who had chronic myelomonocytic leukemia--had FLT3/ITD mutations. 15329908 2004