Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 867
Gene Symbol: CBL
CBL
0.050 GeneticVariation disease BEFREE A mutation analysis of 24 patients with CMML revealed the relationship of GC effectiveness, defined as a monocyte reduction of > 50% within 3 days of methylprednisolone administration, with the MEFV single-nucleotide variant (SNV) and CBL mutation. 29600428 2018
Entrez Id: 867
Gene Symbol: CBL
CBL
0.050 GeneticVariation disease BEFREE Mutations in CBL were found exclusively in overt chronic myelomonocytic leukemia. 28548124 2017
Entrez Id: 867
Gene Symbol: CBL
CBL
0.050 GeneticVariation disease BEFREE We screened 45 patients with chronic myelomonocytic leukemia (n = 39 patients, including seven with transformed-acute myeloid leukemia), MDS/MPN unclassifiable (n = 5), and atypical BCR-ABL1-negative CML (n = 1) for mutations in ASXL1, CBL, NRAS, and TET2 genes by molecular genetics including a sensitive next-generation sequencing (NGS) technique. 24164563 2014
Entrez Id: 867
Gene Symbol: CBL
CBL
0.050 Biomarker disease BEFREE Therefore, CBL(mut) are frequent in chronic myelomonocytic leukemia, absent in classical myeloproliferative neoplasms, and are only exceptionally found in coincidence with JAK-STAT pathway activating mutations. 22733026 2012
Entrez Id: 867
Gene Symbol: CBL
CBL
0.050 GeneticVariation disease BEFREE This finding suggests that alterations of the CBL gene and RUNX1 gene may cooperate in the pathogenesis of CMML in patients with FPD/AML. 22138511 2012