Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3195
Gene Symbol: TLX1
TLX1
0.100 GeneticVariation disease BEFREE G-quadruplex structures formed at the HOX11 breakpoint region contribute to its fragility during t(10;14) translocation in T-cell leukemia. 24001773 2013
Entrez Id: 3195
Gene Symbol: TLX1
TLX1
0.100 AlteredExpression disease BEFREE TLX1/HOX11, a DNA-binding homeodomain protein, was originally identified by virtue of its aberrant expression in T-cell leukemia and subsequently found to be crucial for normal spleen development. 16357834 2006
Entrez Id: 3195
Gene Symbol: TLX1
TLX1
0.100 Biomarker disease BEFREE TALE homeoproteins as HOX11-interacting partners in T-cell leukemia. 11342305 2000
Entrez Id: 3195
Gene Symbol: TLX1
TLX1
0.100 Biomarker disease BEFREE HOX11 is a homeobox-containing oncogene of specific T-cell leukemias. 7596820 1995
Entrez Id: 3195
Gene Symbol: TLX1
TLX1
0.100 AlteredExpression disease BEFREE Two forms of Hox11 a T cell leukemia oncogene, are expressed in fetal spleen but not in primary lymphocytes. 8559142 1995
Entrez Id: 3195
Gene Symbol: TLX1
TLX1
0.100 Biomarker disease BEFREE We have previously cloned two mouse homeobox genes Tlx-1 (T-cell leukemia homeobox gene-1) and a related gene Tlx-2 based on their homology to human HOX11, a putative proto-oncogene involved in human T-cell leukemia. 7698766 1994
Entrez Id: 3195
Gene Symbol: TLX1
TLX1
0.100 AlteredExpression disease BEFREE The findings further suggest that the oncogenic activity of HOX11 might not be restricted to T-cell leukemias in humans. 7905617 1994
Entrez Id: 3195
Gene Symbol: TLX1
TLX1
0.100 Biomarker disease BEFREE Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia. 1676542 1991
Entrez Id: 3195
Gene Symbol: TLX1
TLX1
0.100 Biomarker disease BEFREE The tcl-3 proto-oncogene altered by chromosomal translocation in T-cell leukemia codes for a homeobox protein. 1717256 1991
Entrez Id: 3195
Gene Symbol: TLX1
TLX1
0.100 GeneticVariation disease BEFREE These results suggest that the translocation of the C alpha locus to a putative cellular protooncogene located proximal to the breakpoint at 10q24, for which we propose the name TCL3, results in its deregulation, leading to T-cell leukemia. 2885838 1987