Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 AlteredExpression disease BEFREE Pre-TCR expression cooperates with TEL-JAK2 to transform immature thymocytes and induce T-cell leukemia. 17192390 2007
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 GeneticVariation disease BEFREE Strikingly, profiling of the T-ALLs by clinical, genomic, and large-scale gene expression analyses shows that the TCRB-MYB translocation defines a new T-ALL subtype associated with a very young age for T-cell leukemia (median, 2.2 years) and with a proliferation/mitosis expression signature. 17452517 2007
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 GeneticVariation disease BEFREE In the process of analyzing TCR alpha rearrangements in a patient with adult T-cell leukemia (ATL) carrying a translocation at chromosome 14q11, we found novel complex rearrangements in the Jalpha locus. 11776383 2001
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 Biomarker disease BEFREE Southern blot analysis of T cell receptor (TCR) gene rearrangements has proven to be a helpful tool to establish clonality in T cell leukemias and lymphomas. 10516765 1999
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 GeneticVariation disease BEFREE We characterized the T-cell receptor (TCR) gene rearrangements and sequences in 15 T-lineage acute lymphoblastic leukemia (T-ALL) and seven adult T-cell leukemia (ATL) samples. 9301688 1997
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 GeneticVariation disease BEFREE Human T cell leukemias with continuous V(D)J recombinase activity for TCR-delta gene deletion. 9379030 1997
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 GeneticVariation disease BEFREE The TCL1 oncogene on human chromosome 14q32.1 is involved in chromosome translocations [t(14;14)(q11;q32.1) and t(7;14)(q35;q32.1)] and inversions [inv14(q11;q32.1)] with TCR alpha/beta loci in T-cell leukemias, such as T-prolymphocytic (T-PLL). 7662982 1995
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 GeneticVariation disease BEFREE Although rearrangements of TCR gamma chain genes were shown in single cells of 10 of 10 T-cell leukemias, no rearrangement of these genes was found in single H&RS cells from 13 consecutive patients with HD. 7888676 1995
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 AlteredExpression disease BEFREE These results suggest that the decreased expression of the TCR alpha beta/CD3 complex by ATL cells plays a key role in the development of ATL, irrespective of CD4 expression. 8381310 1993
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 Biomarker disease BEFREE We analyzed the viral integration of human T-cell leukemia virus-I (HTLV-I) and monoclonal rearrangement of T-cell receptor (TCR) gene in blood lymphocytes and the cutaneous infiltrated cells of nine ATL patients with various clinical features and skin eruptions. 1991979 1991
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 AlteredExpression disease BEFREE Examination of the clonalities of these cell lines by the rearrangement profiles of the TCR beta-chain gene and the integration sites of the HTLV-I proviral genome, revealed that two cell lines (KK-1 and KK-5) were of real ATL cell origin. 1861543 1991
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 Biomarker disease BEFREE A deficiency in the rearrangement of proto-oncogene to TCR-alpha may result in only a minor proliferation of abnormal lymphocytes and remain in the preleukemic state of ATL or in the HTLV-I carrier state. 1984842 1991
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 Biomarker disease BEFREE Clinically, the TCR tau delta+ leukemias represented a distinct subgroup of T-cell leukemias. 1826854 1991
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 GeneticVariation disease BEFREE It is possible that translocations in the TCR alpha locus may be involved in ATL. 2169336 1990
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 GeneticVariation disease BEFREE beta and gamma T cell receptor (TCR) gene configuration was studied in 12 patients with large granular lymphocyte T cell leukemia (LGL-leukemia). 2827810 1988
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.100 Biomarker disease BEFREE In an attempt to more accurately define cell lineage we have analyzed cells from patients with B- or T-cell leukemia (n = 26) at various stages of maturation with probes to two additional TCR genes, TCRG and TCRA (encoding the TCR gamma and alpha chains, respectively), as well as the IG heavy chain joining region (IGHJ) and TCRB genes. 3464980 1986