Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3856
Gene Symbol: KRT8
KRT8
0.340 GeneticVariation disease BEFREE Keratin 8 variants are infrequent in patients with alcohol-related liver cirrhosis and do not associate with development of hepatocellular carcinoma. 23078008 2012
Entrez Id: 3856
Gene Symbol: KRT8
KRT8
0.340 Therapeutic disease CTD_human Keratin variants predispose to acute liver failure and adverse outcome: race and ethnic associations. 20538000 2010
Entrez Id: 3856
Gene Symbol: KRT8
KRT8
0.340 GeneticVariation disease LHGDN A specific mutation of keratin 8 (G61C) was found to be a genetic risk factor for the development of cryptogenic liver cirrhosis. 16911694 2006
Entrez Id: 3856
Gene Symbol: KRT8
KRT8
0.340 GeneticVariation disease BEFREE A specific mutation of keratin 8 (G61C) was found to be a genetic risk factor for the development of cryptogenic liver cirrhosis. 16911694 2006
Entrez Id: 3856
Gene Symbol: KRT8
KRT8
0.340 GeneticVariation disease BEFREE Mutation of the cytoskeletal intermediate filament proteins keratin 8 and keratin 18 (K8/K18) is associated with cirrhosis in humans, whereas transgenic mice that overexpress K18 Arg89-->Cys (R89C) have significant predisposition to liver injury. 15726665 2005
Entrez Id: 3856
Gene Symbol: KRT8
KRT8
0.340 GeneticVariation disease BEFREE Keratin 8 and 18 (K8K18) mutations are found in patients with cryptogenic cirrhosis, but the role of keratin mutations in noncryptogenic cirrhosis and the incidence of keratin mutations in the general population are not known. 12724528 2003