Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.370 AlteredExpression disease BEFREE Diesel emissions exposure increased IL-8 secretion and production, antioxidant production, and cytochrome P450 1a1 (CYP1a1) mRNA expression and suppressed superoxide dismutase-1 (SOD1) mRNA expression in bronchial epithelial cells from COPD patients. 30590262 2019
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.370 GeneticVariation disease BEFREE We performed the first comprehensive meta-analysis to summarize the association between CYP1A1 polymorphisms and COPD risk. 26425562 2015
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.370 GeneticVariation disease BEFREE In the present study, we detected the cytochrome P4501A1 gene (CYP1A1) MspI polymorphism and the tumor necrosis factor alpha (TNFα)-308 single nucleotide polymorphism in COPD patients, and investigated their associations with smoking and COPD susceptibility in Inner Mongolia. 24841653 2014
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.370 GeneticVariation disease BEFREE We compared the genotype frequencies of 12 polymorphisms in seven detoxification-related genes (GSTM1, GSTT1, GSTP1 exon 5, CYP1A1 exon 7, CYP1A1 3'-flanking, CYP2E1 intron 6, CYP2E1 5'-flanking, EPHX1 exon 3, EPHX1 exon 4 and HMOX1 promoter) and the hypoxia-related HIF1A (C1772T and G1790A) genes between 48 Japanese patients with work-related COPD who had a working history in a poison gas factory during World War II and two control groups (n=172 and 110 subjects, respectively). 21651746 2013
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.370 GeneticVariation disease BEFREE CYP1A1, CYP1A2 and CYBA gene polymorphisms associated with oxidative stress in COPD. 20080081 2010
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.370 GeneticVariation disease BEFREE The homozygous *2A allele of CYP1A1 is an independent risk factor for very severe COPD. 19507017 2009
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.370 Biomarker disease CTD_human Relation of PON1 and CYP1A1 genetic polymorphisms to clinical findings in a cross-sectional study of a Greek rural population professionally exposed to pesticides. 19022366 2009
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.370 GeneticVariation disease LHGDN We also did not find any association of CYP1A1 gene with COPD in ethnic groups of Bashkortostan. 18389617 2008