| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.380 | Biomarker | disease | BEFREE | However, expressions of nNOS and eNOS did not differ among nonsmokers, smokers with and without COPD. | 26063358 | 2015 | ||||
|
0.380 | GeneticVariation | disease | BEFREE | We aimed to investigate the effects of endothelial nitric oxide synthase (eNOS A/B), angiotensin converting enzyme (ACE I/D) and serotonin transporter (5-HTT L/S) gene polymorphisms on development and severity of PH in COPD patients. | 24057178 | 2013 | ||||
|
0.380 | AlteredExpression | disease | BEFREE | Reduced levels of endothelial NOS (eNOS) and elevated levels of inducible NOS (iNOS) in the skeletal muscle of COPD patients have been recently reported. | 21843929 | 2012 | ||||
|
0.380 | GeneticVariation | disease | BEFREE | ACE and NOS3 genotypes were associated with COPD disease severity, but not with the presence of PH. | 22695028 | 2012 | ||||
|
0.380 | Biomarker | disease | CTD_human | Reduced levels of endothelial NOS (eNOS) and elevated levels of inducible NOS (iNOS) in the skeletal muscle of COPD patients have been recently reported. | 21843929 | 2012 | ||||
|
0.380 | GeneticVariation | disease | LHGDN | Endothelial nitric oxide synthase gene variants contribute to oxidative stress in COPD. | 17658478 | 2007 | ||||
|
0.380 | GeneticVariation | disease | BEFREE | Pulmonary hypertension, a characteristic of chronic obstructive pulmonary disease (COPD) has led us to investigate polymorphisms in angiotensin-converting enzyme (ACE) and endothelial nitric oxide synthase (eNOS) genes. | 15498534 | 2004 | ||||
|
0.380 | AlteredExpression | disease | LHGDN | Expression of neuronal NOS and endothelial NOS isoforms did not differ between control subjects and patients with COPD, whereas no inducible NOS protein expression was detected in limb muscles of the two groups of subjects. | 12816735 | 2003 | ||||
|
0.380 | GeneticVariation | disease | BEFREE | Gene polymorphisms of endothelial nitric oxide synthase enzyme associated with pulmonary hypertension in patients with COPD. | 14682408 | 2003 |