Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3718
Gene Symbol: JAK3
JAK3
0.340 GeneticVariation group BEFREE Janus kinase 3 (JAK3) tyrosine kinase has a central role in the control of lymphopoiesis, and mutations in JAK3 can lead to either severe combined immunodeficiency or leukemia and lymphomas. 30560087 2018
Entrez Id: 3718
Gene Symbol: JAK3
JAK3
0.340 GeneticVariation group BEFREE JAK3 deregulation by activating mutations confers invasive growth advantage in extranodal nasal-type natural killer cell lymphoma. 23689514 2014
Entrez Id: 3718
Gene Symbol: JAK3
JAK3
0.340 GeneticVariation group BEFREE Twelve SNPs were significantly associated with the risk of lymphoma (P(trend)<0.05) in six genes (IL1RN, IL2, IL12RB1, JAK3, TNFRSF13B, and XRCC3). 22524835 2012
Entrez Id: 3718
Gene Symbol: JAK3
JAK3
0.340 Biomarker group BEFREE Moreover, primary lymphoma samples revealed that a number of these genes were reciprocally regulated during disease progression and JAK3 inhibition suggesting that downstream targets of JAK3 could be exploited in the development of novel cancer treatment regimes. 20211620 2010
Entrez Id: 3718
Gene Symbol: JAK3
JAK3
0.340 CausalMutation group CGI