Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 843
Gene Symbol: CASP10
CASP10
0.540 GeneticVariation disease BEFREE These data suggest that the inactivating mutations of the CASP10 gene might lead to the loss of its apoptotic function and contribute to the pathogenesis of some human NHLs. 12010812 2002
Entrez Id: 843
Gene Symbol: CASP10
CASP10
0.540 GeneticVariation disease BEFREE Moreover, the caspase-10 L285F and A414V mutants, found in autoimmune lymphoproliferative syndrome and non-Hodgkin lymphoma, respectively, regulated this necrosis. 27799292 2017
Entrez Id: 843
Gene Symbol: CASP10
CASP10
0.540 GeneticVariation disease BEFREE We investigated five single nucleotide polymorphisms in four key caspase genes, CASP3 [Ex8-280C>A (rs6948) and Ex8+567T>C (rs1049216)], CASP8 Ex14-271A>T (rs13113), CASP9 Ex5+32G>A (rs1052576) and CASP10 Ex3-171A>G (rs3900115) to determine whether they alter risk for non-Hodgkin lymphoma (NHL) in a population-based case-control study of women in Connecticut (461 cases and 535 controls). 17071630 2007
Entrez Id: 843
Gene Symbol: CASP10
CASP10
0.540 GeneticVariation disease LHGDN These data suggest that the inactivating mutations of the CASP10 gene might lead to the loss of its apoptotic function and contribute to the pathogenesis of some human NHLs. 12010812 2002
Entrez Id: 843
Gene Symbol: CASP10
CASP10
0.540 Biomarker disease CTD_human
Entrez Id: 843
Gene Symbol: CASP10
CASP10
0.540 Biomarker disease BEFREE Caspase-10 is an initiation-phase caspase, and somatic mutation of CASP10 that encodes caspase-10 has been found in non-Hodgkin's lymphoma and gastric carcinoma. 20025484 2010
Entrez Id: 843
Gene Symbol: CASP10
CASP10
0.540 CausalMutation disease CGI