Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
0.360 AlteredExpression disease BEFREE Here, we report the subgroup specific expression of PDGFRα and PDGFRβ and their associated biological pathways in MB tumors. c-MYC, a downstream target of PDGFRβ but not PDGFRα, is involved in PDGFRβ signaling associated with cell proliferation, cell death, and invasion. 25576913 2015
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
0.360 AlteredExpression disease BEFREE PDGFRα was strongly expressed on the tumor cells in all three malignancies, while PDGFRβ tumor cell expression was present in the majority of medulloblastoma cases. 24190638 2014
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
0.360 Biomarker disease BEFREE We suggest that coamplification of PDGFRA or VEGFR2 with KIT may be clinically useful novel molecular markers in MBs and PNETs. 19779861 2010
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
0.360 Biomarker disease CTD_human Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma. 19270706 2009
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
0.360 GeneticVariation disease BEFREE A synonymous sequence variation in PDGFRA (CCG to CCA; PRO 567 PRO) was detected in two cases (approximately 7%), but not in 150 normal chromosomes assessed, suggesting that the PDGFRA locus may be associated with medulloblastoma development in certain cases. 16434186 2006
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
0.360 AlteredExpression disease LHGDN Platelet-derived growth factor-B and -C and active alpha-receptors in medulloblastoma cells. 12176024 2002
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
0.360 Biomarker disease BEFREE Inhibitors of PDGFRA and RAS proteins should therefore be considered for investigation as possible novel therapeutic strategies against medulloblastoma. 11544480 2001