Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1141
Gene Symbol: CHRNB2
CHRNB2
0.090 Biomarker disease BEFREE Besides the CHRNA4, CHRNB2 and CHRNA5/A3/B4 cluster on chromosome 15, which has been investigated intensively, recent evidence from both genome-wide association studies and candidate gene-based association studies has revealed the crucial roles of the CHRNB3-CHRNA6 gene cluster on chromosome 8 in nicotine dependence (ND). 27327258 2016
Entrez Id: 1141
Gene Symbol: CHRNB2
CHRNB2
0.090 Biomarker disease BEFREE Since both nicotine dependence (ND) and depressive phenotype are complex disorders, we investigated the effects of a significant early life experience, maternal bonding style (MB) and CHRNB2 gene SNPs on smoking-related depression. 25640319 2015
Entrez Id: 1141
Gene Symbol: CHRNB2
CHRNB2
0.090 GeneticVariation disease BEFREE These findings suggest that CHRNB2 rs4845652 T-allele carriers may be associated with lower levels of ND, and that certain allelic combinations of CHRNA4 and CHRNB2 might be correlated with higher ND levels. 23037950 2013
Entrez Id: 1141
Gene Symbol: CHRNB2
CHRNB2
0.090 Biomarker disease BEFREE Although CHRNB2 alone was not significantly associated with ND in several previously reported association studies on ND, we found it affects ND through interactions with CHRNA4 and NTRK2. 18534558 2008
Entrez Id: 1141
Gene Symbol: CHRNB2
CHRNB2
0.090 GeneticVariation disease BEFREE We found nominally significant (P<0.05) allelic and genotypic association with smoking initiation of SNP rs2072660 and multilocus haplotypes (P<0.007-0.05) in CHRNB2 and nominal (P<0.05) allelic or genotypic association of SNPs in CHRNA7 (rs1909884), CHRNA9 (rs4861065) and CHRNB3 (rs9298629) with nicotine dependence. 16314871 2006
Entrez Id: 1141
Gene Symbol: CHRNB2
CHRNB2
0.090 Biomarker disease BEFREE A similar analysis for the four SNPs within CHRNB2 did not reveal significant association with the three ND measures. 15790597 2005
Entrez Id: 1141
Gene Symbol: CHRNB2
CHRNB2
0.090 GeneticVariation disease BEFREE We studied six single-nucleotide polymorphisms (SNPs) in the CHRNA4 gene and four SNPs in the CHRNB2 gene with respect to nicotine dependence in a collection of 901 subjects (815 siblings and 86 parents) from 222 nuclear families with multiple nicotine-addicted siblings. 15154117 2004
Entrez Id: 1141
Gene Symbol: CHRNB2
CHRNB2
0.090 Biomarker disease BEFREE The beta2-neuronal nicotinic acetylcholine receptor gene (CHRNB2) is a logical candidate for influencing smoking behavior and nicotine dependence. 11906688 2002
Entrez Id: 1141
Gene Symbol: CHRNB2
CHRNB2
0.090 GeneticVariation disease BEFREE However, sequence variations in CHRNB2 have not been reported, and its role in influencing human smoking behavior and nicotine dependence is not known. 11054772 2000