Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
0.350 AlteredExpression disease LHGDN IL-8 might be a malignant factor in human pancreatic cancer by induction of vascular endothelial growth factor and NRP-2 expression and ERK activation. 18307536 2008
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
0.350 Biomarker disease CTD_human Interleukin-8 increases vascular endothelial growth factor and neuropilin expression and stimulates ERK activation in human pancreatic cancer. 18307536 2008
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
0.350 Biomarker disease LHGDN IL-8 has an effect on the pancreatic cancer cells in an autocrine manner. 16525644 2006
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
0.350 AlteredExpression disease BEFREE Thus, c-Src regulates critical "downstream" signaling pathways that contribute to expression of IL-8 in human pancreatic tumor cells, suggesting c-Src may be a target for therapeutic intervention in pancreatic adenocarcinoma. 16103072 2005
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
0.350 Biomarker disease LHGDN GSK3 and PKB/Akt have roles in the integrin-mediated regulation of PTHrP, IL-6 and IL-8 in pancreatic cancer 15609321 2005
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
0.350 AlteredExpression disease LHGDN IL-8 regulates MMP-2 activity and plays an important role in the invasiveness of human pancreatic cancer 12632066 2003