Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.340 Biomarker disease BEFREE In this study, we describe the ability of the urokinase-type plasminogen activator receptor (uPAR) promoter to efficiently and selectively target pancreatic tumors and metastases, which enables the successful management of pancreatic cancer. 19484141 2009
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.340 AlteredExpression disease LHGDN Interaction between cancer cells and stromal fibroblasts is required for activation of the uPAR-uPA-MMP-2 cascade in pancreatic cancer metastasis. 17545513 2007
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.340 AlteredExpression disease LHGDN Interleukin-1alpha enhances the aggressive behavior of pancreatic cancer cells by regulating the alpha6beta1-integrin and urokinase plasminogen activator receptor expression. 16504015 2006
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.340 Biomarker disease BEFREE Localization of uPA within normal and pancreatic tumor sections was subsequently confirmed using immunohistochemistry. 15683429 2005
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
0.340 Biomarker disease CTD_human These results show that uPA is one of the downstream target genes induced by constitutively activated RelA in human pancreatic tumor cells, and suggests that constitutive RelA activity may play a critical role in tumor invasion and metastasis. 10467400 1999