Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3284
Gene Symbol: HSD3B2
HSD3B2
0.340 Biomarker disease BEFREE In summary , our data revealed that GATA1 is an important transcription factor activating the HSD3B2 promoter in steroidogenesis, and baicalin potentially be an effective therapeutic agent for hyperandrogenism in PCOS by inhibiting the recruitment of GATA1 to the HSD3B2 promoter in ovarian tissue. 30650063 2019
Entrez Id: 3284
Gene Symbol: HSD3B2
HSD3B2
0.340 Biomarker disease BEFREE Expression of FSHR (P < 0.05), AR (P < 0.05), and CYP11A1 (P < 0.05) was lower, and expression of CYP19A1 (P < 0.05), STAR (P < 0.05), HSD3B2 (P = NS), and INHBA (P < 0.05) was higher in PCO GCs. 31276164 2019
Entrez Id: 3284
Gene Symbol: HSD3B2
HSD3B2
0.340 Biomarker disease BEFREE A Dietary Medium-Chain Fatty Acid, Decanoic Acid, Inhibits Recruitment of Nur77 to the HSD3B2 Promoter In Vitro and Reverses Endocrine and Metabolic Abnormalities in a Rat Model of Polycystic Ovary Syndrome. 26465200 2016
Entrez Id: 3284
Gene Symbol: HSD3B2
HSD3B2
0.340 Biomarker disease BEFREE Therefore, specific downregulation of HSD3B2 at adrenarche around age 6-8 years and characteristic upregulation of HSD3B2 in the ovaries of women suffering from the polycystic ovary syndrome remain unexplained prompting us to study the regulation of HSD3B2 in adrenal NCI-H295R cells. 23874725 2013
Entrez Id: 3284
Gene Symbol: HSD3B2
HSD3B2
0.340 Biomarker disease CTD_human The expression of sex steroid synthesis and inactivation enzymes in subcutaneous adipose tissue of PCOS patients. 22381227 2012