Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.510 Therapeutic group RGD Antioxidants and tumor necrosis factor alpha-inhibiting activity of sesame oil against doxorubicin-induced cardiotoxicity. 24441175 2014
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.510 GeneticVariation group BEFREE T-cells from CHF patients showed enhanced gene expression of chemokines, ligands in the tumor necrosis factor superfamily, as well as the inflammatory cytokines interferon-gamma and interleukin-18 with similar pattern in ischemic (n=5) and idiopathic cardiomyopathy (n=9). 14522416 2003
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.510 Biomarker group CTD_human Peripartum cardiomyopathy: analysis of clinical outcome, left ventricular function, plasma levels of cytokines and Fas/APO-1. 10716473 2000
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3 		0.310 Biomarker group BEFREE TNNI3 is the third most important disease gene in this cohort and complete loss of TNNI3 leads to severe pediatric CMP. 31568572 2019
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.310 Therapeutic group CTD_human Type 5 adenylyl cyclase increases oxidative stress by transcriptional regulation of manganese superoxide dismutase via the SIRT1/FoxO3a pathway. 23536361 2013
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3 		0.310 Biomarker group CTD_human In vitro and in vivo examination of cardiac troponins as biochemical markers of drug-induced cardiotoxicity. 17587482 2007
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.310 GeneticVariation group BEFREE To reveal genetic risk factors of nonfamilial idiopathic cardiomyopathy (IDC) in Japanese, polymorphisms in the SOD2 and HLA-DRB1 genes were investigated in 86 patients and 380 healthy controls. 10425186 1999
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.300 Biomarker group CTD_human The preventive effects of edible folic acid on cardiomyocyte apoptosis and survival in early onset triple-transgenic Alzheimer's disease model mice. 29068127 2018
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		0.300 Biomarker group CTD_human The preventive effects of edible folic acid on cardiomyocyte apoptosis and survival in early onset triple-transgenic Alzheimer's disease model mice. 29068127 2018
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker group CTD_human The preventive effects of edible folic acid on cardiomyocyte apoptosis and survival in early onset triple-transgenic Alzheimer's disease model mice. 29068127 2018
Entrez Id: 6444
Gene Symbol: SGCD
SGCD 		0.300 Biomarker group CTD_human Hydrogen gas attenuates embryonic gene expression and prevents left ventricular remodeling induced by intermittent hypoxia in cardiomyopathic hamsters. 25281567 2014
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		0.300 Therapeutic group CTD_human Opposing roles of Akt and STAT3 in the protection of the maternal heart from peripartum stress. 24448315 2014
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		0.300 Biomarker group CTD_human Opposing roles of Akt and STAT3 in the protection of the maternal heart from peripartum stress. 24448315 2014
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		0.300 Biomarker group CTD_human Opposing roles of Akt and STAT3 in the protection of the maternal heart from peripartum stress. 24448315 2014
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2 		0.300 Biomarker group CTD_human Disruption of type 5 adenylyl cyclase prevents β-adrenergic receptor cardiomyopathy: a novel approach to β-adrenergic receptor blockade. 25193472 2014
Entrez Id: 467
Gene Symbol: ATF3
ATF3 		0.300 Therapeutic group CTD_human Characterization of the regulatory mechanisms of activating transcription factor 3 by hypertrophic stimuli in rat cardiomyocytes. 25136830 2014
Entrez Id: 111
Gene Symbol: ADCY5
ADCY5 		0.300 Biomarker group CTD_human Type 5 adenylyl cyclase increases oxidative stress by transcriptional regulation of manganese superoxide dismutase via the SIRT1/FoxO3a pathway. 23536361 2013
Entrez Id: 57724
Gene Symbol: EPG5
EPG5 		0.300 Biomarker group CTD_human Recessive mutations in EPG5 cause Vici syndrome, a multisystem disorder with defective autophagy. 23222957 2013
Entrez Id: 1756
Gene Symbol: DMD
DMD 		0.300 Therapeutic group CTD_human Intolerance to ß-blockade in a mouse model of δ-sarcoglycan-deficient muscular dystrophy cardiomyopathy. 20675662 2010
Entrez Id: 116
Gene Symbol: ADCYAP1
ADCYAP1 		0.300 Therapeutic group CTD_human Cardioprotective effect of endogenous pituitary adenylate cyclase-activating polypeptide on Doxorubicin-induced cardiomyopathy in mice. 20378996 2010
Entrez Id: 57381
Gene Symbol: RHOJ
RHOJ 		0.300 Biomarker group CTD_human Comparative phenotypic assessment of cardiac pathology, physiology, and gene expression in C3H/HeJ, C57BL/6J, and B6C3F1/J mice. 21037199 2010
Entrez Id: 142
Gene Symbol: PARP1
PARP1 		0.300 Biomarker group CTD_human Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1. 20561897 2010
Entrez Id: 5164
Gene Symbol: PDK2
PDK2 		0.300 Biomarker group CTD_human Comparative phenotypic assessment of cardiac pathology, physiology, and gene expression in C3H/HeJ, C57BL/6J, and B6C3F1/J mice. 21037199 2010
Entrez Id: 1756
Gene Symbol: DMD
DMD 		0.300 Biomarker group CTD_human Intolerance to ß-blockade in a mouse model of δ-sarcoglycan-deficient muscular dystrophy cardiomyopathy. 20675662 2010
Entrez Id: 5563
Gene Symbol: PRKAA2
PRKAA2 		0.300 Biomarker group CTD_human Comparative phenotypic assessment of cardiac pathology, physiology, and gene expression in C3H/HeJ, C57BL/6J, and B6C3F1/J mice. 21037199 2010