Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.600 Biomarker group MGD
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.600 Biomarker group MGD
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
0.540 Biomarker group MGD
Entrez Id: 324
Gene Symbol: APC
APC
0.520 Biomarker group MGD
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.500 Biomarker group MGD
Entrez Id: 1316
Gene Symbol: KLF6
KLF6
0.400 Biomarker group CTD_human
Entrez Id: 4601
Gene Symbol: MXI1
MXI1
0.360 Biomarker group CTD_human
Entrez Id: 10664
Gene Symbol: CTCF
CTCF
0.310 GeneticVariation group UNIPROT
Entrez Id: 8379
Gene Symbol: MAD1L1
MAD1L1
0.300 Biomarker group CTD_human
Entrez Id: 367
Gene Symbol: AR
AR
0.600 Biomarker group BEFREE Unusual specificity of the androgen receptor in the human prostate tumor cell line LNCaP: high affinity for progestagenic and estrogenic steroids. 2322591 1990
Entrez Id: 367
Gene Symbol: AR
AR
0.600 Biomarker group BEFREE To study the role of the androgen receptor in androgen-dependent and androgen-independent prostate tumor cell growth, androgen receptor mRNA expression was monitored in six different human prostate tumor cell lines and tumors, which were grown either in vitro or by transplantation on (male) nude mice. 2285596 1990
Entrez Id: 1950
Gene Symbol: EGF
EGF
0.400 AlteredExpression group BEFREE Since EGF has also been found in prostatic tissues, the enhanced expression of the EGF-R gene may play a role in the growth of prostate tumors, possibly by an autocrine pathway. 1692888 1990
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
0.310 GeneticVariation group BEFREE Two mutations were detected: an A----G transition causing a glutamine to arginine amino acid substitution at codon 61 of the Ha-ras gene in a primary prostatic duct adenocarcinoma and a G----T transversion causing a glycine to valine amino acid substitution at codon 12 of the Ha-ras gene in a prostate tumor cell line (TSU-PR1) derived from a lymph node metastasis. 2208148 1990
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
0.010 GeneticVariation group BEFREE Twenty-four primary prostate tumors (23 acinar tumors and one ductal tumor) and five prostate tumor cell lines were examined for mutations at codons 12, 13, and 61 of the Ki-ras, Ha-ras, and N-ras genes. 2208148 1990
Entrez Id: 57126
Gene Symbol: CD177
CD177
0.010 AlteredExpression group BEFREE Since EGF has also been found in prostatic tissues, the enhanced expression of the EGF-R gene may play a role in the growth of prostate tumors, possibly by an autocrine pathway. 1692888 1990
Entrez Id: 354
Gene Symbol: KLK3
KLK3
0.400 AlteredExpression group BEFREE Expression of prostate-specific antigen (PA) mRNA was tested at various time periods after incubation of the human prostate tumor cell line LNCaP with the synthetic androgen R1881. 1724287 1991
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.070 GeneticVariation group BEFREE The MDR1 gene messenger ribonucleic acid (mRNA) was detected in two tumors using the Chinese hamster probe (one sphenoid wing meningioma and one metastatic prostate tumor) and in one CNS lymphoma using the human probe. 1682428 1991
Entrez Id: 23158
Gene Symbol: TBC1D9
TBC1D9
0.010 GeneticVariation group BEFREE The MDR1 gene messenger ribonucleic acid (mRNA) was detected in two tumors using the Chinese hamster probe (one sphenoid wing meningioma and one metastatic prostate tumor) and in one CNS lymphoma using the human probe. 1682428 1991
Entrez Id: 367
Gene Symbol: AR
AR
0.600 Biomarker group BEFREE The human prostate tumor cell line LNCaP contains an abnormal androgen receptor system with broad steroid binding specificity. 1562539 1992
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
0.260 Biomarker group BEFREE We have expressed the single MMP matrilysin in the tumorigenic but nonmetastatic human prostate tumor cell line DU-145 to determine if matrilysin has a functional role in prostate tumor cell invasion. 8417833 1993
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.500 AlteredExpression group BEFREE Furthermore, our data demonstrate phenotypic similarity between prostate tumors and high grade PIN at the level of EGFR protein expression. 7521960 1994
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.500 Biomarker group BEFREE Elevated levels of epidermal growth factor (EGF) and epidermal growth factor receptor (EGF-R) have been demonstrated in prostate cancer cell lines and clinical specimens suggesting a role for polypeptide growth factors in prostate tumor cell growth and invasion. 8290389 1994
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.400 GeneticVariation group BEFREE Our results show that p53 mutations are infrequent in both primary and metastatic prostate tumors. 8314337 1994
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.400 Biomarker group BEFREE Our data provide evidence that IL6 may play a role in the growth of benign and malignant prostate tumors and suggest that the IL6 receptor could be a target for the delivery of therapeutic agents in prostate cancer. 7512667 1994
Entrez Id: 1950
Gene Symbol: EGF
EGF
0.400 Biomarker group BEFREE Our primary objectives were to: 1) develop a system for the study of prostatic tumor evolution; and 2) examine the role of the epidermal growth factor/epidermal growth factor receptor (EGF/EGFR) pathway in prostate tumor progression. 8077059 1994