×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
Biomarker
group
BEFREE
The study concludes that rfhSP-D induces apoptosis in prostate tumor explants as well as in androgen dependent and independent prostate cancer cells via p53 and pAkt pathways.
31355132
2019
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
Biomarker
group
CTD_human
Cribriform and intraductal prostate cancer are associated with increased genomic instability and distinct genomic alterations.
29295717
2018
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
Biomarker
group
CTD_human
The long tail of oncogenic drivers in prostate cancer.
29610475
2018
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
Biomarker
group
BEFREE
These findings suggest that EAF2 and p53 functionally interact in prostate tumor suppression and that simultaneous inactivation of EAF2 and p53 can drive prostate carcinogenesis.
29029019
2017
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
Biomarker
group
BEFREE
Loss of Skp2 resulted in a striking decrease of Ezh2 levels in Pten/Trp53 double-null MEFs and in prostate tumors of Pten/Trp53 double-null mutant mice.
27869166
2017
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
Biomarker
group
BEFREE
Importantly, we find that pharmacological inhibition of γ-secretase promotes growth arrest in both Pten-null and Pten/Trp53 -null prostate tumours by triggering cellular senescence.
27941799
2016
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
AlteredExpression
group
BEFREE
Expressions of CD24 and mutant p53 were more frequently observed in late-stage and metastatic prostate tumors .
26712693
2016
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
Biomarker
group
CTD_human
Spatial genomic heterogeneity within localized, multifocal prostate cancer.
26005866
2015
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
Biomarker
group
CTD_human
Integrative molecular profiling of routine clinical prostate cancer specimens.
25735316
2015
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
Biomarker
group
BEFREE
Met was amplified in 67% of prostate tumors from Pten p53 prostate conditional null mice and in approximately 30% of metastatic human prostate cancer specimens, often in association with loss of PTEN and TP53 .
25381262
2015
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
Biomarker
group
BEFREE
Murine double minute 2 siRNA and wild-type p53 gene therapy interact positively with zinc on prostate tumours in vitro and in vivo.
24447832
2014
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
Biomarker
group
BEFREE
Targeted deletion of the signaling domain of β4 inhibited prostate tumor growth and progression in response to loss of p53 and Rb function in a mouse model of prostate cancer (PB-TAg mice).
23348745
2013
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
AlteredExpression
group
BEFREE
Analysis of prostate tumors has shown a direct expression correlation between sGCα1 and p53 .
22174378
2012
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
Biomarker
group
BEFREE
A subset of 64 prostate tumors was stained immunohistochemically for P53 .
21778786
2011
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
AlteredExpression
group
BEFREE
We demonstrated that human prostate tumors had increased expression of MDM2 and mutant p53 proteins.
21444629
2011
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
Biomarker
group
CTD_human
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility.
21946351
2011
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
Biomarker
group
CTD_human
Association between polymorphisms of TP53 and MDM2 and prostate cancer risk in southern Chinese.
20875869
2010
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
Biomarker
group
BEFREE
Gossypol induces apoptosis by activating p53 in prostate cancer cells and prostate tumor -initiating cells.
20124455
2010
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
GeneticVariation
group
LHGDN
Our aim was to determine the frequency of KLF6 and TP53 mutations in a well-defined group of prostate tumors with different stages and Gleason grades.
19020536
2008
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
GeneticVariation
group
LHGDN
Clinical significance of p53 alterations in surgically treated prostate cancers.
18552821
2008
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
GeneticVariation
group
BEFREE
Our aim was to determine the frequency of KLF6 and TP53 mutations in a well-defined group of prostate tumors with different stages and Gleason grades.
19020536
2008
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
GeneticVariation
group
LHGDN
TP53 mutation in prostate needle biopsies--comparison with patients follow-up.
18225585
2008
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
GeneticVariation
group
LHGDN
Paclitaxel enhanced radiation sensitization for the suppression of human prostate cancer tumor growth via a p53 independent pathway.
17823933
2007
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
AlteredExpression
group
LHGDN
Theaflavins induced apoptosis of LNCaP cells is mediated through induction of p53, down-regulation of NF-kappa B and mitogen-activated protein kinases pathways.
17499812
2007
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.400
AlteredExpression
group
LHGDN
Expression of androgen receptor is negatively regulated by p53.
18084622
2007