Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
0.850 Biomarker disease BEFREE With strong evidence (p-value ≤0.000001), the triplet (MAGI2, CRBLCrus1.L, FBXO28) is a significant biomarker for schizophrenia patients. 30184473 2018
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
0.850 GeneticVariation disease GWASCAT Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia. 28991256 2017
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
0.850 AlteredExpression disease BEFREE Ndel1 enzyme activity was significantly lower in patients with SCZ (t=4.9; p<0.001) and was found to be associated with CAMK1D, MAGI2, CCDC25, and GABGR3, at a level of suggestive significance (p<10(-6)), independent of the clinical status. 26851141 2016
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
0.850 GeneticVariation disease GWASCAT Genome-wide association study of schizophrenia in Ashkenazi Jews. 26198764 2015
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
0.850 Biomarker disease CTD_human One of the rare CNVs found in SZ cohorts is the duplication of Synaptic Scaffolding Molecule (S-SCAM, also called MAGI-2), which encodes a postsynaptic scaffolding protein controlling synaptic AMPA receptor levels, and thus the strength of excitatory synaptic transmission. 25653350 2015
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
0.850 Biomarker disease PSYGENET One of the rare CNVs found in SZ cohorts is the duplication of Synaptic Scaffolding Molecule (S-SCAM, also called MAGI-2), which encodes a postsynaptic scaffolding protein controlling synaptic AMPA receptor levels, and thus the strength of excitatory synaptic transmission. 25653350 2015
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
0.850 GeneticVariation disease BEFREE In conclusion, although we could not detect strong genetic evidence for association of common variants in MAGI2 and increased schizophrenia risk in a Japanese population, these SNPs may increase risk of cognitive impairment in schizophrenic patients. 22649501 2012
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
0.850 Biomarker disease PSYGENET In conclusion, although we could not detect strong genetic evidence for association of common variants in MAGI2 and increased schizophrenia risk in a Japanese population, these SNPs may increase risk of cognitive impairment in schizophrenic patients. 22649501 2012
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
0.850 Biomarker disease PSYGENET Because earlier work had identified a CNV in the close relative MAGI2 in SZ, the study was extended to include MAGI2. 22381734 2012
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
0.850 Biomarker disease BEFREE Because earlier work had identified a CNV in the close relative MAGI2 in SZ, the study was extended to include MAGI2. 22381734 2012
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
0.850 Biomarker disease BEFREE A recent study has reported that MAGI1, MAGI2, and protein tyrosine phosphatase, receptor-type, Z polypeptide 1 (PTPRZ1; located on 7q31.3) gene products regulate the NRG1-ERBB4 signaling pathway, and PTPRZ1 is associated with schizophrenia in a Caucasian population. 18186075 2008
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
0.850 Biomarker disease MGD