Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
0.130 GeneticVariation disease BEFREE Our results demonstrated that TNFAIP3 rs10499194 polymorphism may be associated with a reduced risk of AS. 31308453 2019
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
0.130 Biomarker disease BEFREE Our objective was to study the role and mechanism of TNFAIP3 in ankylosing spondylitis. 29940800 2018
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
0.130 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
0.130 Biomarker disease BEFREE Psoriasis and psoriatic arthritis fall into this disease spectrum, with the largest region of susceptibility coming from the MHC (most likely HLA-C, ie, C*06:02 although additional influences are also being implicated), and most of the other genetic susceptibility coming from genes involved in cytokine production, specifically genes in the Th17 pathway (IL-12B, IL-23A and IL-23R, the latter, like in AS, not seen in Asians), genes in the nuclear factor κB pathway (TNFAIP3 and TNIP1) and genes in the Th2 pathway (IL-4 and IL-13). 21339218 2011