Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 GeneticVariation group BEFREE The proinflammatory cytokine IL-1β plays a crucial role in the development of gastric tumors and polymorphisms in the IL-1 gene cluster leading to increased IL-1β production have been associated with increased risk for gastric cancer. 25172489 2014
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 Biomarker group CTD_human Capsaicin consumption, Helicobacter pylori CagA status and IL1B-31C>T genotypes: a host and environment interaction in gastric cancer. 22414649 2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 Biomarker group CTD_human 15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer. 19584167 2009
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 GeneticVariation group LHGDN The genotype of IL-1B3954 T/T may protect against gastric cancer and gastric ulcer in Chinese Han population. 19102413 2009
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 GeneticVariation group LHGDN Report IL-1beta gene polymorphisms in gastric cancer cases'and controls'family members from Chinese areas at high cancer prevalence. 18565646 2008
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 GeneticVariation group BEFREE To investigate whether the genotyping of IL-1B-511/IL-1RN polymorphisms is useful to characterize atrophic body gastritis patients at increased risk for gastric neoplasms. 18047563 2008
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 GeneticVariation group LHGDN IL-1B-511 T allele is associated with H.pylori infection in non-cardiac gastric cancer in a Chinese population/IL-1B-511 gene polymorphism appears to play an important role in gastric carcinogenesis in Chinese patients with H.pylori infection 17295877 2007
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 Biomarker group LHGDN IL1-BETA SNPs 0794C > T, 1274C > T, and 2143T > C are associated with gastric cancer. 17196954 2007
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 GeneticVariation group LHGDN In a meta-analysis, the overall associations between IL-1B proinflammatory polymorphisms and gastric cancer were null but several studies showed an association/sources of this variation are unclear. 17035400 2007
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 GeneticVariation group LHGDN The IL-1B+3954 T allele is a major risk for cachexia from locally advanced gastric cancer. 17359523 2007
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 GeneticVariation group LHGDN The association between the interleukin-1 polymorphisms and gastric cancer risk depends on the family history of gastric carcinoma in the study population. 16454826 2006
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 GeneticVariation group LHGDN In countries with a low prevalence of gastric cancer, risk groups carrying cagA+ strains and IL-1 genetic polymorphisms should be identified and treated. 17006981 2006
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 Biomarker group CTD_human Implication of peroxisome proliferator-activated receptor gamma and proinflammatory cytokines in gastric carcinogenesis: link to Helicobacter pylori-infection. 15492468 2005
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 Biomarker group LHGDN epistatic interrelationship between IL-1beta -511 and IL-1RN confers protection against gastric cancer in low-risk Italian population 15927855 2005
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 GeneticVariation group LHGDN In a Mexican population, the IL-1B proinflammatory genotype increases the risk of distal gastric cancer. 15540224 2005
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 GeneticVariation group LHGDN These findings indicate that these two IL-1B promoter variants may contribute to the risk of developing gastric cancer in the Chinese population, especially in individuals with H.pylori infection. 15488638 2004
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 GeneticVariation group LHGDN Polymorphisms in interleukin (IL) -1 beta and its endogenous receptor antagonist are associated with risk of Helicobacter pylori-related gastric cancer 12730860 2003
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 AlteredExpression group LHGDN IL-1beta down-regulates TFF expression in human stomach neoplasm cells cultivated in vitro. 12297725 2003
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 GeneticVariation group LHGDN Polymorphism of the promoter is found in Dutch patients with stomach neoplasms and Epstein-Barr virus. 14566840 2003
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.400 GeneticVariation group LHGDN The polymorphism of promotor region -31C/T of IL-1B gene is associated with the susceptibility of gastric cancer in Chinese. 12133467 2002