Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2147
Gene Symbol: F2
F2
0.580 GeneticVariation phenotype LHGDN Prothrombin G20210A gene variant is not associated with idiopathic portal vein thrombosis in an area endemic for portal vein thrombosis. 16283309 2006
Entrez Id: 2147
Gene Symbol: F2
F2
0.580 GeneticVariation phenotype LHGDN A single-base change (G to A) at position 20210 in the 3' untranslated region of the prothrombin gene is associated with increased plasma levels of prothrombin and might therefore increase the risk for thrombosis. 12865818 2003
Entrez Id: 2147
Gene Symbol: F2
F2
0.580 GeneticVariation phenotype LHGDN Group 1: A total of 377 children with thrombosis were analyzed during 7 years between January 1997 and 2004 and screened for prothrombin G20210A mutation. 16020118 2005
Entrez Id: 2147
Gene Symbol: F2
F2
0.580 GeneticVariation phenotype LHGDN The G20210A prothrombin gene, factor V Leiden, and MTHFR C677T mutations have been identified as predisposing genetic factors for thrombosis. 15958894 2005
Entrez Id: 2147
Gene Symbol: F2
F2
0.580 GeneticVariation phenotype LHGDN The results indicate that FV Leiden prevalence is quite high and coexistence of FV Leiden with other hereditary causes of thrombosis such as prothrombin G20210A mutation and MTHFR enzyme defect is not rare in healthy population of Aegean region of Turkey. 17456626 2007
Entrez Id: 2147
Gene Symbol: F2
F2
0.580 GeneticVariation phenotype LHGDN A 10-year-old boy with basilar artery thrombosis who was heterozygous for prothrombin G20210A mutation is described. 17621506 2007
Entrez Id: 2153
Gene Symbol: F5
F5
0.380 GeneticVariation phenotype LHGDN Factor V(LEIDEN) and cardiopulmonary bypass: investigation of haemostatic parameters and the effect of aprotinin using an ex vivo model. 11761087 2001
Entrez Id: 2153
Gene Symbol: F5
F5
0.380 GeneticVariation phenotype LHGDN Absence of factor V Arg306--Thr and low factor V Arg306->Gly mutation prevalence in Thai blood donors. 15691154 2004
Entrez Id: 2153
Gene Symbol: F5
F5
0.380 GeneticVariation phenotype LHGDN Functional characterization of factor V-Ile359Thr: a novel mutation associated with thrombosis. 14695241 2004
Entrez Id: 2153
Gene Symbol: F5
F5
0.380 GeneticVariation phenotype LHGDN These data suggested that the factor V Leiden mutation might be a risk factor for the development of thrombosis in Behcet's disease patients. 12632020 2003
Entrez Id: 2153
Gene Symbol: F5
F5
0.380 GeneticVariation phenotype LHGDN The G20210A prothrombin gene, factor V Leiden, and MTHFR C677T mutations have been identified as predisposing genetic factors for thrombosis. 15958894 2005
Entrez Id: 5624
Gene Symbol: PROC
PROC
0.340 GeneticVariation phenotype LHGDN The data from this model predict an increased risk of perioperative thrombosis due to inhibition of APC function in cardiac surgical patients heterozygous for the F5L mutation. 11761087 2001
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
0.340 GeneticVariation phenotype LHGDN The 4G allele is associated with higher levels of PAI-1, and might increase the risk for intravascular thrombosis. 17949795 2008
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
0.340 GeneticVariation phenotype LHGDN Among the eight PTFEG patients with thrombosis, seven were PAI 4G/5G. 18609532 2008
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
0.340 GeneticVariation phenotype LHGDN PAI-1 gene 4G/5G genotype: A risk factor for thrombosis in vessels of internal organs. 12353306 2002
Entrez Id: 5624
Gene Symbol: PROC
PROC
0.340 GeneticVariation phenotype LHGDN Factor V Leiden, prothrombin G20210A, and protein C mutation frequency in Turkish venous thrombosis patients. 18160601 2008
Entrez Id: 5624
Gene Symbol: PROC
PROC
0.340 GeneticVariation phenotype LHGDN These data indicate that individuals carrying the 4600AG genotype have high sEPCR levels but do not have an increased risk of thrombosis, whereas individuals carrying the 4678CC genotype have higher APC levels and lower risk of venous thromboembolism. 15116250 2004
Entrez Id: 10544
Gene Symbol: PROCR
PROCR
0.330 GeneticVariation phenotype LHGDN This review highlights the different mutations/polymorphisms reported in the EPCR gene and their association with the risk of thrombosis. 17849044 2007
Entrez Id: 10544
Gene Symbol: PROCR
PROCR
0.330 GeneticVariation phenotype LHGDN Contribution of polymorphisms in the endothelial protein C receptor gene to soluble endothelial protein C receptor and circulating activated protein C levels, and thrombotic risk. 15116250 2004
Entrez Id: 11093
Gene Symbol: ADAMTS13
ADAMTS13
0.320 GeneticVariation phenotype LHGDN A new name in thrombosis, ADAMTS13. 12195022 2002
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.310 GeneticVariation phenotype LHGDN These data suggest that the TNF-alpha -308 A allele is associated with increased PTFE graft thrombosis and failure in hemodialysis patients. 12580317 2003
Entrez Id: 350
Gene Symbol: APOH
APOH
0.250 GeneticVariation phenotype LHGDN Valine/valine genotype at position 247 of the beta2-glycoprotein I gene in Mexican patients with primary antiphospholipid syndrome: association with anti-beta2-glycoprotein I antibodies. 12571857 2003
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.100 GeneticVariation phenotype LHGDN The results showed that (1) an increased leukocyte count at diagnosis was associated with thrombosis during follow-up ("baseline analysis," relative risk [RR] 2.3, 95% confidence interval [CI] 1.4-3.9, P = .001); (2) hydroxyurea (HU) lowered leukocytosis and reduced the strength of the association between leukocytosis and thrombosis ("time-dependent analysis," RR 1.6, 95% CI 0.9-2.0, not significant [NS]); (3) the association of leukocytosis and thrombosis was more evident in untreated low-risk patients (RR 2.7, 95% CI 1.2-6.4, P = .01) compared with HU-treated high-risk patients (RR 1.6, 95% CI 0.8-3.2, NS); and (4) the presence of JAK2 V617F was not identified as a risk factor for thrombosis during follow-up despite a significant association between the mutation and leukocytosis. 17110452 2007
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.100 GeneticVariation phenotype LHGDN JAK2V617F mutation in patients with portal vein thrombosis. 18343999 2008
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.100 GeneticVariation phenotype LHGDN The association of JAK2V617F mutation and leukocytosis with thrombotic events in essential thrombocythemia. 17920754 2007