Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 64805
Gene Symbol: P2RY12
P2RY12 		0.500 Biomarker phenotype RGD Comparison of ticagrelor and thienopyridine P2Y(12) binding characteristics and antithrombotic and bleeding effects in rat and dog models of thrombosis/hemostasis. 19692114 2009
Entrez Id: 64805
Gene Symbol: P2RY12
P2RY12 		0.500 Biomarker phenotype CTD_human Glycoprotein Ibalpha inhibition and ADP receptor antagonists, but not aspirin, reduce platelet thrombus formation in flowing blood exposed to atherosclerotic plaques. 17334511 2007
Entrez Id: 5328
Gene Symbol: PLAU
PLAU 		0.500 Therapeutic phenotype CTD_human [Preparation of thrombus-targeted urokinase liposomes and its thrombolytic effect in model rats]. 12830724 2003
Entrez Id: 5328
Gene Symbol: PLAU
PLAU 		0.500 Therapeutic phenotype CTD_human Pulmonary emboli from pulse-spray and mechanical thrombolysis: evaluation with an animal dialysis-graft model. 8657906 1996
Entrez Id: 2243
Gene Symbol: FGA
FGA 		0.500 Biomarker phenotype CTD_human Molecular basis for fibrinogen Dusart (A alpha 554 Arg-->Cys) and its association with abnormal fibrin polymerization and thrombophilia. 8473507 1993
Entrez Id: 5328
Gene Symbol: PLAU
PLAU 		0.500 Therapeutic phenotype CTD_human Urokinase and AT-III concentrate treatment in inferior vena cava thrombosis associated with nephrotic syndrome. 2133253 1990
Entrez Id: 5328
Gene Symbol: PLAU
PLAU 		0.500 Therapeutic phenotype CTD_human [Treatment of massive arterial thrombosis caused by thrombocytopenia induced by heparin with local thrombolysis]. 2106299 1990
Entrez Id: 5328
Gene Symbol: PLAU
PLAU 		0.500 Therapeutic phenotype CTD_human Intraoperative infusion of lytic drugs for thrombotic complications of revascularization. 2795766 1989
Entrez Id: 5328
Gene Symbol: PLAU
PLAU 		0.500 Therapeutic phenotype CTD_human The urokinase-pulmonary embolism trial. 4884574 1969
Entrez Id: 2243
Gene Symbol: FGA
FGA 		0.500 Biomarker phenotype GENOMICS_ENGLAND
Entrez Id: 2153
Gene Symbol: F5
F5 		0.380 AlteredExpression phenotype LHGDN Factor V Leiden causing activated protein C resistance is the most common inherited form of thrombophilia leading to thrombosis. 17456626 2007
Entrez Id: 2153
Gene Symbol: F5
F5 		0.380 Biomarker phenotype LHGDN The roles of factor V Hong Kong (FV Hong Kong), factor V Leiden (FV Leiden), factor II G20210A (FII G20210A), methylenetetrahydrofolate reductase (MTHFR) C677T, and MTHFR A1298C mutations in Turkish patients with thrombosis (270 patients) compared with healthy controls (114 subjects) were evaluated. 17911197 2007
Entrez Id: 2153
Gene Symbol: F5
F5 		0.380 Biomarker phenotype LHGDN ABO blood group genotypes and the risk of venous thrombosis: effect of factor V Leiden. 15634288 2005
Entrez Id: 2153
Gene Symbol: F5
F5 		0.380 GeneticVariation phenotype LHGDN The G20210A prothrombin gene, factor V Leiden, and MTHFR C677T mutations have been identified as predisposing genetic factors for thrombosis. 15958894 2005
Entrez Id: 2153
Gene Symbol: F5
F5 		0.380 GeneticVariation phenotype LHGDN Absence of factor V Arg306--Thr and low factor V Arg306->Gly mutation prevalence in Thai blood donors. 15691154 2004
Entrez Id: 2153
Gene Symbol: F5
F5 		0.380 GeneticVariation phenotype LHGDN Functional characterization of factor V-Ile359Thr: a novel mutation associated with thrombosis. 14695241 2004
Entrez Id: 2153
Gene Symbol: F5
F5 		0.380 GeneticVariation phenotype LHGDN These data suggested that the factor V Leiden mutation might be a risk factor for the development of thrombosis in Behcet's disease patients. 12632020 2003
Entrez Id: 2153
Gene Symbol: F5
F5 		0.380 GeneticVariation phenotype LHGDN Factor V(LEIDEN) and cardiopulmonary bypass: investigation of haemostatic parameters and the effect of aprotinin using an ex vivo model. 11761087 2001
Entrez Id: 2153
Gene Symbol: F5
F5 		0.380 Biomarker phenotype CTD_human Although larger studies are required, this case report suggests that thrombomodulin gene mutations could be an additional genetic risk factor for thrombosis in carriers of the factor V Leiden mutation. 11132655 2000
Entrez Id: 2153
Gene Symbol: F5
F5 		0.380 Biomarker phenotype CTD_human Lipoprotein (a): its role in childhood thromboembolism. 9164807 1997
Entrez Id: 2152
Gene Symbol: F3
F3 		0.340 Biomarker phenotype CTD_human Reduced thrombosis in Klkb1-/- mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor. 25339356 2015
Entrez Id: 7450
Gene Symbol: VWF
VWF 		0.340 Biomarker phenotype CTD_human Vascular and thrombogenic effects of pulmonary exposure to Libby amphibole. 22352330 2012
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		0.340 Biomarker phenotype CTD_human Aorta mRNA expression for biomarkers of oxidative stress (HO-1, LOX-1), inflammation (MIP-2), and thrombosis (tPA, PAI-1, vWf) were increased at baseline in SH and SHHF relative to WKY. 22352330 2012
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		0.340 GeneticVariation phenotype LHGDN The 4G allele is associated with higher levels of PAI-1, and might increase the risk for intravascular thrombosis. 17949795 2008
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		0.340 GeneticVariation phenotype LHGDN Among the eight PTFEG patients with thrombosis, seven were PAI 4G/5G. 18609532 2008