Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.050 Biomarker disease BEFREE CSF nerve growth factor (β-NGF) is increased but CSF insulin-like growth factor-(IGF-1) is normal in children with tuberous sclerosis and infantile spasms. 30503720 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.050 Biomarker disease BEFREE Examples of the latter include mGluR5 antagonists in FXS, mTOR inhibitors in TSC and insulin-like growth factor 1 (IGF-1) in PMS. 25695134 2015
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.050 Biomarker disease BEFREE Our results show that an EGF independent pathway is more important than that involving IGF-I for growth and survival of TSC(-/-) ASM cells, and such EGF-dependency is the result of the lack of tuberin. 18958173 2008
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.050 Biomarker disease BEFREE Insulin-like growth factor-I plays a key role in this balance by activating the Akt/tuberous sclerosis complex 2/mammalian target of rapamycin pathway. 18193272 2008
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.050 Biomarker disease BEFREE The autocrine release of IGF-1 may therefore be a powerful mechanism of survival of the tightly packed cells in the thick-walled vessels of TSC angiomyolipoma and in lymphangioleiomyomatosis (LAM) nodules. 17592551 2007